1.0 2016-05-26 05:13:06 UTC 2026-05-14 17:50:11 UTC NADP SmallMolecule NADP is an organic compound with the chemical formula C21H29N7O17P3. NADP belongs to the (5'->5')-dinucleotides, a class of nucleosides, nucleotides, and analogues within the organic compounds. With an average molecular weight of 744.41 g/mol, NADP is a heavy molecule. This compound is found in or released from 13 recorded sources across several diverse sectors. In the realm of electrical and electronic equipment, it is associated with antennas, amplifiers, electrodes, radio transmission systems, and conductors or conductive bodies characterised by the conductive materials. Within the food, food processing and cookware sector, it is linked to food preservation and the preparation of vinegar, wort, and wine or sparkling wine. Additionally, NADP is found in household cleaning and consumer products, specifically in soap detergents, cigar cigarettes, and tobacco smoke filters. Finally, it is recorded as being released from building and construction sources, specifically tents or canopies. NADP+ C21H29N7O17P3 744.4129 744.083277073 1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium 1-[(2R,3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium 53-59-8 NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 XJLXINKUBYWONI-NNYOXOHSSA-O Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues L-alpha-amino acids Amino acids Carbonyl compounds Carboxylic acids Fatty acids and conjugates Hydrocarbon derivatives Hydroxamic acids Monoalkylamines Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Aliphatic acyclic compound Amine Amino acid Carbonyl group Carboxylic acid Fatty acid Hydrocarbon derivative Hydroxamic acid L-alpha-amino acid Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Aliphatic acyclic compounds Detected and Not Quantified Glutamate Metabolism SMP0000072 Glutathione Metabolism SMP0000015 Arginine and Proline Metabolism SMP0000020 beta-Alanine Metabolism SMP0000007 Degradation of Superoxides SMP0000468 Ethanol Degradation SMP0000449 Fatty Acid Elongation in Mitochondria SMP0000054 Folate Metabolism SMP0000053 Fructose and Mannose Degradation SMP0000064 Lysine Degradation SMP0000037 Histidine Metabolism SMP0000044 Arachidonic Acid Metabolism SMP0000075 Androgen and Estrogen Metabolism SMP0000068 Steroid Biosynthesis SMP0000023 Purine Metabolism SMP0000050 Pyruvate Metabolism SMP0000060 Pentose Phosphate Pathway SMP0000031 17-beta Hydroxysteroid Dehydrogenase III Deficiency SMP0000356 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency SMP0000243 Homocarnosinosis SMP0000385 Hyperinsulinism-Hyperammonemia Syndrome SMP0000339 Glutathione Synthetase Deficiency SMP0000337 5-Oxoprolinuria SMP0000143 Adenosine Deaminase Deficiency SMP0000144 Adenylosuccinate Lyase Deficiency SMP0000167 Gout or Kelley-Seegmiller Syndrome SMP0000365 Lesch-Nyhan Syndrome (LNS) SMP0000364 Molybdenum Cofactor Deficiency SMP0000203 Xanthine Dehydrogenase Deficiency (Xanthinuria) SMP0000220 Purine Nucleoside Phosphorylase Deficiency SMP0000210 AICA-Ribosiduria SMP0000168 Prolidase Deficiency (PD) SMP0000207 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency) SMP0000362 Hyperprolinemia Type II SMP0000360 Hyperprolinemia Type I SMP0000361 Prolinemia Type II SMP0000208 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency) SMP0000188 Ornithine Aminotransferase Deficiency (OAT Deficiency) SMP0000363 Smith-Lemli-Opitz Syndrome (SLOS) SMP0000389 CHILD Syndrome SMP0000387 Desmosterolosis SMP0000386 Chondrodysplasia Punctata II, X-Linked Dominant (CDPX2) SMP0000388 Lysosomal Acid Lipase Deficiency (Wolman Disease) SMP0000319 GABA-Transaminase Deficiency SMP0000351 gamma-Glutamyltransferase Deficiency SMP0000183 Glutaric Aciduria Type I SMP0000186 Saccharopinuria/Hyperlysinemia II SMP0000239 Histidinemia SMP0000191 Leigh Syndrome SMP0000196 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) SMP0000334 Pyruvate Dehydrogenase Complex Deficiency SMP0000212 Leukotriene C4 Synthesis Deficiency SMP0000353 Piroxicam Action Pathway SMP0000077 Ibandronate Action Pathway SMP0000079 Simvastatin Action Pathway SMP0000082 Acetylsalicylic Acid Action Pathway SMP0000083 Etodolac Action Pathway SMP0000084 Ketoprofen Action Pathway SMP0000085 Ibuprofen Action Pathway SMP0000086 Rofecoxib Action Pathway SMP0000087 Pravastatin Action Pathway SMP0000089 Rosuvastatin Action Pathway SMP0000092 Diclofenac Action Pathway SMP0000093 Sulindac Action Pathway SMP0000094 Alendronate Action Pathway SMP0000095 Celecoxib metabolism Pathway SMP0000096 Ketorolac Action Pathway SMP0000098 Pterine Biosynthesis SMP0000005 Steroidogenesis SMP0000130 Tyrosine Metabolism SMP0000006 Glycerolipid Metabolism SMP0000039 Bile Acid Biosynthesis SMP0000035 Sphingolipid Metabolism SMP0000034 Nicotinate and Nicotinamide Metabolism SMP0000048 Transfer of Acetyl Groups into Mitochondria SMP0000466 Pyrimidine Metabolism SMP0000046 Tryptophan Metabolism SMP0000063 Retinol Metabolism SMP0000074 Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency SMP0000373 Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH SMP0000371 Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency SMP0000372 Alkaptonuria SMP0000169 Hawkinsinuria SMP0000190 Tyrosinemia Type I SMP0000218 beta-Ureidopropionase Deficiency SMP0000172 UMP Synthase Deficiency (Orotic Aciduria) SMP0000219 Dihydropyrimidinase Deficiency SMP0000178 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) SMP0000202 Congenital Bile Acid Synthesis Defect Type II SMP0000314 Congenital Bile Acid Synthesis Defect Type III SMP0000318 Zellweger Syndrome SMP0000316 Cerebrotendinous Xanthomatosis (CTX) SMP0000315 Gaucher Disease SMP0000349 Globoid Cell Leukodystrophy SMP0000348 Metachromatic Leukodystrophy (MLD) SMP0000347 Glycerol Kinase Deficiency SMP0000187 Vitamin A Deficiency SMP0000336 2-Hydroxyglutric Aciduria (D and L Form) SMP0000136 Hypercholesterolemia SMP0000209 Cyclophosphamide Action Pathway SMP0000447 Ifosfamide Action Pathway SMP0000448 Tamoxifen Action Pathway SMP0000471 Suprofen Action Pathway SMP0000101 Bromfenac Action Pathway SMP0000102 Indomethacin Action Pathway SMP0000104 Mefenamic Acid Action Pathway SMP0000109 Oxaprozin Action Pathway SMP0000113 Nabumetone Action Pathway SMP0000114 Naproxen Action Pathway SMP0000120 Diflunisal Action Pathway SMP0000289 Azathioprine Action Pathway SMP0000427 Mercaptopurine Action Pathway SMP0000428 Methotrexate Action Pathway SMP0000432 Lovastatin Action Pathway SMP0000099 Zoledronate Action Pathway SMP0000107 Cerivastatin Action Pathway SMP0000111 Risedronate Action Pathway SMP0000112 Pamidronate Action Pathway SMP0000117 Fluvastatin Action Pathway SMP0000119 Meloxicam Action Pathway SMP0000106 Valdecoxib Action Pathway SMP0000116 Phenytoin (Antiarrhythmic) Action Pathway SMP0000327 Lidocaine (Antiarrhythmic) Action Pathway SMP0000328 Lidocaine (Local Anaesthetic) Action Pathway SMP0000398 Imipramine SMP0000422 Desipramine Action Pathway SMP0000423 Thioguanine Action Pathway (old) SMP0000430 Nicotine Action Pathway SMP0000431 Disulfiram Action Pathway SMP0000429 DOPA-Responsive Dystonia SMP0000486 Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency SMP0000487 Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps) SMP0000488 Hyperphenylalaninemia Due to DHPR-Deficiency SMP0000489 Segawa Syndrome SMP0000490 Sepiapterin Reductase Deficiency SMP0000491 Carnosinuria, Carnosinemia SMP0000493 Tyrosinemia, Transient, of the Newborn SMP0000494 Dopamine beta-Hydroxylase Deficiency SMP0000498 5-Oxoprolinase Deficiency SMP0000500 gamma-Glutamyltranspeptidase Deficiency SMP0000501 Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency SMP0000504 Hyperornithinemia with Gyrate Atrophy (HOGA) SMP0000505 Hyperornithinemia-Hyperammonemia-Homocitrullinuria (HHH-syndrome) SMP0000506 L-Arginine:Glycine Amidinotransferase Deficiency SMP0000507 Cholesteryl Ester Storage Disease SMP0000508 Hyper-IgD Syndrome SMP0000509 Mevalonic Aciduria SMP0000510 Wolman Disease SMP0000511 Xanthinuria Type I SMP0000512 Xanthinuria Type II SMP0000513 Glucose-6-phosphate Dehydrogenase Deficiency SMP0000518 Ribose-5-phosphate Isomerase Deficiency SMP0000519 Transaldolase Deficiency SMP0000520 Fabry Disease SMP0000525 Krabbe Disease SMP0000526 Hyperlysinemia I, Familial SMP0000527 Hyperlysinemia II or Saccharopinuria SMP0000528 D-Glyceric Acidura SMP0000529 Familial Lipoprotein Lipase Deficiency SMP0000530 Monoamine Oxidase-A Deficiency (MAO-A) SMP0000533 Adenine Phosphoribosyltransferase Deficiency (APRT) SMP0000535 Mitochondrial DNA Depletion Syndrome-3 SMP0000536 Myoadenylate Deaminase Deficiency SMP0000537 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) SMP0000543 Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD) SMP0000544 Primary Hyperoxaluria II, PH2 SMP0000558 Pyruvate Kinase Deficiency SMP0000559 Fructosuria SMP0000561 Aromatase Deficiency SMP0000565 17-alpha-Hydroxylase Deficiency (CYP17) SMP0000566 Succinic Semialdehyde Dehydrogenase Deficiency SMP0000567 Pyridoxine Dependency with Seizures SMP0000571 11-beta-Hydroxylase Deficiency (CYP11B1) SMP0000575 21-Hydroxylase Deficiency (CYP21) SMP0000576 Corticosterone Methyl Oxidase I Deficiency (CMO I) SMP0000577 Corticosterone Methyl Oxidase II Deficiency (CMO II) SMP0000578 Ibuprofen Metabolism Pathway SMP0000590 Cyclophosphamide Metabolism Pathway SMP0000604 Ifosfamide Metabolism Pathway SMP0000605 Tamoxifen Metabolism Pathway SMP0000606 Lidocaine (Local Anaesthetic) Metabolism Pathway SMP0000620 Imipramine SMP0000625 Desipramine Metabolism Pathway SMP0000626 Nicotine Metabolism Pathway SMP0000628 Felbamate Metabolism Pathway SMP0000633 Carbamazepine Metabolism Pathway SMP0000634 Valproic Acid Metabolism Pathway SMP0000635 Clomipramine Pathway SMP0000639 Doxepin Metabolism Pathway SMP0000641 Nevirapine Metabolism Pathway SMP0000642 Celecoxib metabolism Pathway SMP0000644 Doxorubicin Metabolism Pathway SMP0000650 Rosiglitazone Metabolism Pathway SMP0000653 Aerobic Glycolysis (Warburg Effect) SMP0000654 Antipyrine Action Pathway SMP0000692 Antrafenine Action Pathway SMP0000693 Carprofen Action Pathway SMP0000694 Etoricoxib Action Pathway SMP0000695 Fenoprofen Action Pathway SMP0000696 Flurbiprofen Action Pathway SMP0000697 Magnesium Salicylate Action Pathway SMP0000698 Lumiracoxib Action Pathway SMP0000699 Lornoxicam Action Pathway SMP0000700 Phenylbutazone Action Pathway SMP0000701 Nepafenac Action Pathway SMP0000702 Trisalicylate-Choline Action Pathway SMP0000703 Tolmetin Action Pathway SMP0000704 Tiaprofenic Acid Action Pathway SMP0000705 Tenoxicam Action Pathway SMP0000706 Salsalate Action Pathway SMP0000707 Salicylate-Sodium Action Pathway SMP0000708 Salicylic Acid Action Pathway SMP0000709 Acetaminophen Action Pathway SMP0000710 Apparent Mineralocorticoid Excess Syndrome SMP0000717 3-beta-Hydroxysteroid Dehydrogenase Deficiency SMP0000718 2-Aminoadipic 2-Oxoadipic Aciduria SMP0000719 27-Hydroxylase Deficiency SMP0000720 Folate Malabsorption, Hereditary SMP0000724 Fructose Intolerance, Hereditary SMP0000725 The Oncogenic Action of 2-Hydroxyglutarate SMP0002291 The Oncogenic Action of Succinate SMP0002292 The Oncogenic Action of Fumarate SMP0002295 Glutaminolysis and Cancer SMP0002298 The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria SMP0002358 The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria SMP0002359 Androstenedione Metabolism SMP0030406 Estrone Metabolism SMP0030880 NAD+ Signalling Pathway (Cancer) SMP0083297 NAD+ Signalling and Aging SMP0084271 LPS and Citrate Signaling and Inflammation SMP0100046 Mevalonate Pathway SMP0121055 Bloch Pathway (Cholesterol Biosynthesis) SMP0121057 Kandutsch-Russell Pathway (Cholesterol Biosynthesis) SMP0121060 Isoniazid Metabolism SMP0121102 Fluorouracil Metabolism SMP0121111 Atorvastatin Action Pathway SMP0000131 Prednisolone Action Action Pathway New SMP0122639 Alendronate Action Pathway (New) SMP0122691 Disulfiram Aldehyde Dehydrogenase Inhibitor Action Pathway SMP0122693 Cyclophosphamide Action Pathway (New) SMP0122835 Metabolism and Physiological Effects of Phenylacetylglutamine SMP0123208 Ifosfamide Alkylating Agent Action Pathway SMP0124478 Atorvastatin Action Pathway (New) SMP0124555 Fluvastatin Action Pathway (New) SMP0124569 Lovastatin Action Pathway (New) SMP0124570 Pravastatin Action Pathway (New) SMP0124576 Rosuvastatin SMP0124577 Simvastatin Action Pathway (New) SMP0124578 Tamoxifen Anti-Cancer Action Pathway SMP0124698 Metabolism and Physiological Effects of Oxalic acid SMP0124875 Carbimazole Action Pathway SMP0124888 Itaconate Immunometabolism Pathway SMP0124904 Succinate Immunometabolism Pathway SMP0124909 Citrate Immunometabolism Pathway SMP0124912 Prednisone Anti-inflammatory Action Pathway SMP0125039 Fluconazole Action Pathway SMP0125079 Propofol Metabolism SMP0125095 Fluconazole Metabolism SMP0125098 Itraconazole Action Pathway SMP0125099 Itraconazole Metabolism SMP0125100 Clotrimazole Action Pathway SMP0125104 Terbinafine Action Pathway SMP0125118 Terbinafine Metabolism SMP0125122 Finasteride Action Pathway SMP0125125 Ketoconazole Anti-fungal Action Pathway SMP0125162 Fentanyl Metabolism SMP0125222 Cocaine metabolism SMP0125265 Caffeine Vasodilation Action Pathway SMP0125283 Fenofibrate Metabolism Pathway SMP0125319 Bupropion Metabolism SMP0125320 Naltrexone Metabolism SMP0125328 Levodopa Metabolism Pathway SMP0125329 Haloperidol Metabolism Pathway SMP0125333 Carbamazepine Metabolism Pathway SMP0125359 Tolnaftate Action Pathway SMP0125360 Nicotine Metabolism Pathway SMP0125386 Econazole Action Pathway SMP0125404 Oxiconazole Action Pathway SMP0125405 Bifonazole Action Pathway SMP0125418 Sertaconazole Action Pathway SMP0125419 Terconazole Action Pathway SMP0125439 Tioconazole Action Pathway SMP0125440 Voriconazole Action Pathway SMP0125441 Voriconazole Metabolism SMP0125454 T Cell Exhaustion SMP0125467 Immunometabolism Pathway (Bacterial Activation) SMP0125484 Immunometabolism Pathway (Viral Activation) SMP0125488 Viral Sepsis SMP0125490 Bacterial Sepsis SMP0125493 Metabolsim and Physiological Effects of Argininic acid SMP0125504 Metabolism and Physiological Effects of 3-Deoxyglucosone SMP0125516 Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine SMP0125530 Metabolism and Physiological Effects of 4-Hydroxyhippuric Acid SMP0125537 Metabolsim and Physiological Effects of 4-Ethylphenylsulfate SMP0125541 Zidovudine Metabolism SMP0125559 Etoricoxib Metabolism SMP0125575 Doxorubicin Metabolism SMP0125576 DOPA-Responsive Dystonia SMP0125582 Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency SMP0125583 Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps) SMP0125585 Hyperphenylalaninemia Due to DHPR-Deficiency SMP0125586 Segawa Syndrome SMP0125587 Sepiapterin Reductase Deficiency SMP0125588 Hawkinsinuria SMP0125590 Tyrosinemia Type I SMP0125591 Tyrosinemia, Transient, of the Newborn SMP0125592 Dopamine beta-Hydroxylase Deficiency SMP0125594 Monoamine Oxidase-A Deficiency (MAO-A) SMP0125595 GABA-Transaminase Deficiency: beta-alanine SMP0125596 beta-Aminoisobutyric Aciduria SMP0125597 Carnosinuria, Carnosinemia SMP0125598 Phenylketonuria SMP0125602 Glutathione Synthetase Deficiency SMP0125614 5-Oxoprolinuria SMP0125615 gamma-Glutamyltransferase Deficiency SMP0125616 5-Oxoprolinase Deficiency SMP0125617 gamma-Glutamyltranspeptidase Deficiency SMP0125618 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency) SMP0125623 Hyperprolinemia Type II SMP0125624 Hyperprolinemia Type I SMP0125626 Prolinemia Type II SMP0125627 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency) SMP0125628 Ornithine Aminotransferase Deficiency (OAT Deficiency) SMP0125629 Hyperornithinemia with Gyrate Atrophy (HOGA) SMP0125630 Hyperornithinemia-Hyperammonemia-Homocitrullinuria (HHH-syndrome) SMP0125633 L-Arginine:Glycine Amidinotransferase Deficiency SMP0125634 Smith-Lemli-Opitz Syndrome (SLOS) SMP0125635 CHILD Syndrome SMP0125637 Desmosterolosis SMP0125638 Chondrodysplasia Punctata II, X-Linked Dominant (CDPX2) SMP0125639 Lysosomal Acid Lipase Deficiency (Wolman Disease) SMP0125640 Hypercholesterolemia SMP0125641 Hyper-IgD Syndrome SMP0125642 Mevalonic Aciduria SMP0125643 Glucose-6-phosphate Dehydrogenase Deficiency SMP0125653 Ribose-5-phosphate Isomerase Deficiency SMP0125654 Transaldolase Deficiency SMP0125655 Gaucher Disease SMP0125685 Globoid Cell Leukodystrophy SMP0125686 Metachromatic Leukodystrophy (MLD) SMP0125687 Fabry Disease SMP0125688 Congenital Bile Acid Synthesis Defect Type II SMP0125689 Congenital Bile Acid Synthesis Defect Type III SMP0125690 Familial Hypercholanemia (FHCA) SMP0125695 Zellweger Syndrome SMP0125696 Cerebrotendinous Xanthomatosis (CTX) SMP0125697 Glutaric Aciduria Type I (Lysine Degradation) SMP0125698 Saccharopinuria/Hyperlysinemia II SMP0125699 Hyperlysinemia I, Familial SMP0125700 Pyridoxine Dependency with Seizures SMP0125701 2-Aminoadipic 2-Oxoadipic Aciduria SMP0125703 Glycerol Kinase Deficiency SMP0125704 D-Glyceric Aciduria SMP0125705 Familial Lipoprotein Lipase Deficiency SMP0125706 Histidinemia SMP0125711 beta-Ureidopropionase Deficiency SMP0125716 UMP Synthase Deficiency (Orotic Aciduria) SMP0125717 Dihydropyrimidinase Deficiency SMP0125719 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) SMP0125720 Adenosine Deaminase Deficiency SMP0125721 Adenylosuccinate Lyase Deficiency SMP0125722 Gout or Kelley-Seegmiller Syndrome SMP0125723 Molybdenum Cofactor Deficiency SMP0125725 Xanthinuria Type I SMP0125727 Purine Nucleoside Phosphorylase Deficiency SMP0125728 Xanthinuria Type II SMP0125731 Adenine Phosphoribosyltransferase Deficiency (APRT) SMP0125732 Mitochondrial DNA Depletion Syndrome-3 SMP0125734 Myoadenylate Deaminase Deficiency SMP0125735 Folate Malabsorption, Hereditary SMP0125747 Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (Fatty Acid Elongation in Mitochondria) SMP0125748 Leigh Syndrome SMP0125770 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) SMP0125771 Pyruvate Dehydrogenase Complex Deficiency SMP0125772 Primary Hyperoxaluria II, PH2 SMP0125773 Pyruvate Kinase Deficiency SMP0125774 Fructosuria SMP0125775 Fructose Intolerance, Hereditary SMP0125776 17-beta Hydroxysteroid Dehydrogenase III Deficiency SMP0125781 Aromatase Deficiency SMP0125782 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency SMP0125784 Homocarnosinosis SMP0125785 Hyperinsulinism-Hyperammonemia Syndrome SMP0125787 Vitamin A Deficiency SMP0125788 Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency SMP0125797 Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH SMP0125798 Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency SMP0125799 11-beta-Hydroxylase Deficiency (CYP11B1) SMP0125800 Corticosterone Methyl Oxidase I Deficiency (CMO I) SMP0125801 Corticosterone Methyl Oxidase II Deficiency (CMO II) SMP0125802 3-beta-Hydroxysteroid Dehydrogenase Deficiency SMP0125804 Butenafine Action Pathway SMP0125811 Butoconazole Action Pathway SMP0125812 Efinaconazole Action Pathway SMP0125813 Isavuconazole Action Pathway SMP0125814 Isavuconazonium Action Pathway SMP0125818 Isoconazole Action Pathway SMP0125819 Luliconazole Action Pathway SMP0125821 Miconazole Action Pathway SMP0125822 Naftifine Action Pathway SMP0125827 Oteseconazole Action Pathway SMP0125830 Posaconazole Action Pathway SMP0125831 Sulconazole Action Pathway SMP0125832 Alclometasone Action Pathway SMP0126158 Amcinonide Action Pathway SMP0126169 Beclomethasone dipropionate Action Pathway SMP0126172 Betamethasone Action Pathway SMP0126176 Betamethasone phosphate Action Pathway SMP0126180 Budesonide Action Pathway SMP0126182 Ciclesonide Action Pathway SMP0126184 Clobetasol propionate Action Pathway SMP0126191 Clobetasone Action Pathway SMP0126192 Clocortolone Action Pathway SMP0126193 Cortisone Acetate Action Pathway SMP0126207 Deflazacort Action Pathway SMP0126212 Desonide Action Pathway SMP0126223 Desoximetasone Action Pathway SMP0126224 Dexamethasone Action Pathway SMP0126226 Diflorasone Action Pathway SMP0126227 Flumethasone Action Pathway SMP0126233 Fluocinonide Action Pathway SMP0126234 Flurandrenolide Action Pathway SMP0126235 Methyl Prednisolone Action Pathway SMP0126236 Hydrocortamate Action Pathway SMP0126237 Prednicarbate Action Pathway SMP0126238 Ulobetasol Action Pathway SMP0126240 Fluocinolone acetonide Action Pathway SMP0126241 Methotrexate Action Pathway (new) SMP0126242 Fluticasone Action Pathway SMP0126244 Prednisolone Phosphate Action Pathway SMP0126245 Prednisolone acetate MOA Action Pathway SMP0126246 Fluticasone furoate Action Pathway SMP0126248 Fluticasone propionate Action Pathway SMP0126249 Hydrocortisone Action Pathway SMP0126250 Triamcinolone Action Pathway SMP0126251 Flunisolide Action Pathway SMP0126252 Rimexolone Action Pathway SMP0126253 Difluprednate Action Pathway SMP0126254 Fluorometholone Action Pathway SMP0126255 Medrysone Action Pathway SMP0126256 Loteprednol etabonate Action Pathway SMP0126258 Pemetrexed Action Pathway SMP0126261 Levoleucovorin Action Pathway SMP0126269 Pralatrexate Action Pathway SMP0126296 Raltitrexed Action Pathway SMP0126304 Pafolacianine Action Pathway SMP0126305 Clodronic Acid Action Pathway SMP0126307 Alendronate Action Pathway (New Revised) SMP0126316 Ibandronate Action Pathway SMP0126317 Pamidronate Action Pathway (new) SMP0126321 Risedronate Action Pathway (new) SMP0126323 Zoledronate Action Pathway SMP0126324 Etidronic Acid Action Pathway SMP0126349 Tiludronic Acid Action Pathway SMP0126351 Clemastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0126421 Ticlopidine Action Pathway (new) SMP0126467 Dutasteride Action Pathway SMP0126518 Carmustine Action Pathway (New) SMP0126591 Mitomycin Action Pathway SMP0126602 Pitavastatin Action Pathway SMP0126665 Doxylamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0126731 Sulfanilamide Action Pathway SMP0126777 Metabolism and Physiological Effects of Androsterone sulfate SMP0127012 Mirtazapine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174980 Dexbrompheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174981 Triprolidine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174982 Cyproheptadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174983 Hydroxyzine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174984 Cinnarizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174985 Azatadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174986 Meclizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174987 Carbinoxamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174988 Tripelennamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174989 Brompheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174990 Ketotifen H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174991 Promethazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174992 Mequitazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174993 Diphenhydramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174994 Emedastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174995 Cyclizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174996 Alimemazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174997 Phenindamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174998 Pheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174999 Methapyrilene H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175000 Levocetirizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175001 Mepyramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175002 Alcaftadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175003 Antazoline H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175004 Chloropyramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175005 Dimetindene H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175006 Acrivastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175007 Ebastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175008 Oxatomide H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175009 Dexchlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175010 Bepotastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175011 Buclizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175012 Methdilazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175013 Diphenylpyraline H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175014 Bromodiphenhydramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175015 Olanzapine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175016 Clozapine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175017 Doxepin H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175018 Orphenadrine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175019 Quetiapine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175020 Isothipendyl H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175022 Chlorcyclizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175023 Bilastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175024 Rupatadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175025 Thonzylamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175026 Propiomazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175027 Deptropine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175028 Cetirizine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175029 Loratadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175030 Fexofenadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175031 Desloratadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175032 Terfenadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175033 Astemizole H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175034 Olopatadine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175035 Azelastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175036 Levocabastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175037 Mizolastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175038 Epinastine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175039 Dimenhydrinate H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175041 Chlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175042 Mianserin H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175043 Esmirtazapine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175044 Dimetotiazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175045 Dexchlorpheniramine maleate H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175046 GSK-1004723 H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175047 Ziprasidone H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175049 Promazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175050 Trazodone H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175051 Clofedanol H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175053 Chlorprothixene H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175054 Chlorpromazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175059 Zuclopenthixol H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175061 Butriptyline H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175063 Cariprazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175064 Benzquinamide H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175067 Aceprometazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175068 Aripiprazole lauroxil H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0175069 Ferroptosis SMP0575898 Glutaric Acidemia Type I (GA-I) SMP0658920 Relaxin I Signaling Pathway SMP0689895 Ovarian Steroidogenesis SMP0728344 logp -11 logp -0.78 ALOGPS logs -2.27 ALOGPS solubility 4.15e+00 g/l ALOGPS logp -10 ChemAxon pka_strongest_acidic 0.66 ChemAxon pka_strongest_basic 4 ChemAxon iupac 1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium ChemAxon average_mass 744.4129 ChemAxon mono_mass 744.083277073 ChemAxon smiles NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O ChemAxon formula C21H29N7O17P3 ChemAxon inchi InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 ChemAxon inchikey XJLXINKUBYWONI-NNYOXOHSSA-O ChemAxon polar_surface_area 364.79 ChemAxon refractivity 152.87 ChemAxon polarizability 60.89 ChemAxon rotatable_bond_count 13 ChemAxon acceptor_count 17 ChemAxon donor_count 9 ChemAxon physiological_charge -3 ChemAxon formal_charge 1 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226a12760> DB03461 5886