1.0 2016-05-26 05:33:01 UTC 2026-05-14 16:59:02 UTC Prostaglandin I2 SmallMolecule Prostaglandin I2 is an organic compound with the formula C20H32O5 and an average molecular weight of 352.47 g/mol. Prostaglandin I2 belongs to the eicosanoids, a subclass of fatty acyls within the organic compounds. It is classified under the superclass of lipids and lipid-like molecules. The compound is found in or released from healthcare, pharmaceuticals, and veterinary products, specifically as antithrombotic agents, and is administered via intravenous exposure. Prostaglandin I2 interacts with three recorded protein targets: the prostacyclin receptor (PTGIR), prostacyclin synthase (PTGIS), and the P2Y purinoceptor 12 (P2RY12), for which it acts as an agonist or inducer. epoprostenol C20H32O5 352.4651 352.224974134 5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid epoprostenol 35121-78-9 CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 KAQKFAOMNZTLHT-OZUDYXHBSA-N Organic compounds Lipids and lipid-like molecules Fatty Acyls Eicosanoids Prostaglandins and related compounds Carbonyl compounds Carboxylic acids Cyclic alcohols and derivatives Fatty alcohols Heterocyclic fatty acids Hydrocarbon derivatives Hydroxy fatty acids Medium-chain fatty acids Medium-chain hydroxy acids and derivatives Monocarboxylic acids and derivatives Organic oxides Oxacyclic compounds Secondary alcohols Tetrahydrofurans Alcohol Aliphatic heteropolycyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Cyclic alcohol Fatty alcohol Heterocyclic fatty acid Hydrocarbon derivative Hydroxy fatty acid Medium-chain fatty acid Medium-chain hydroxy acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Prostaglandin skeleton Secondary alcohol Tetrahydrofuran Aliphatic heteropolycyclic compounds Prostaglandins Prostaglandins prostaglandins I Detected and Not Quantified Epoprostenol Drug Metabolism Action Pathway SMP0143658 logp 2.42 logp 3.83 ALOGPS logs -3.41 ALOGPS solubility 1.36e-01 g/l ALOGPS logp 2.42 ChemAxon pka_strongest_acidic 4.43 ChemAxon pka_strongest_basic -1.6 ChemAxon iupac 5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid ChemAxon average_mass 352.4651 ChemAxon mono_mass 352.224974134 ChemAxon smiles CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O ChemAxon formula C20H32O5 ChemAxon inchi InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 ChemAxon inchikey KAQKFAOMNZTLHT-OZUDYXHBSA-N ChemAxon polar_surface_area 86.99 ChemAxon refractivity 99.01 ChemAxon polarizability 41.47 ChemAxon rotatable_bond_count 10 ChemAxon acceptor_count 5 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf0872098> DB01240 5462154 28589780 BE0000110 BE0000475 BE0000117