1.0 2016-05-26 06:42:52 UTC 2026-08-20 00:37:06 UTC Rabeprazole SmallMolecule Rabeprazole is an organic compound with the chemical formula C18H21N3O3S and an average molecular weight of 359.44 g/mol. Rabeprazole belongs to the sulfinylbenzimidazoles, a subclass of benzimidazoles within the organic compounds. It is categorized as an organoheterocyclic compound. The compound is found in or released from ten recorded sources. These include healthcare, pharmaceuticals and veterinary products, specifically drugs for acid related disorders, and food, food processing and cookware for food preservation. It is also associated with household cleaning and consumer products, specifically other smoking requisites, and electrical and electronic equipment, including electrodes, magnets, amplifiers, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices, among two others. The recorded route of exposure for this compound is oral. In terms of its biological activity, rabeprazole acts on one recorded protein target, functioning as an inhibitor of Potassium-transporting ATPase alpha chain 1 (ATP4A). C18H21N3O3S 359.443 359.130362243 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole rabeprazole 117976-89-3 COCCCOC1=C(C)C(CS(=O)C2=NC3=CC=CC=C3N2)=NC=C1 InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21) YREYEVIYCVEVJK-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzimidazoles Sulfinylbenzimidazoles Sulfinylbenzimidazoles Alkyl aryl ethers Azacyclic compounds Benzenoids Dialkyl ethers Heteroaromatic compounds Hydrocarbon derivatives Imidazoles Methylpyridines Organic oxides Organonitrogen compounds Organopnictogen compounds Sulfinyl compounds Sulfoxides Alkyl aryl ether Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Dialkyl ether Ether Heteroaromatic compound Hydrocarbon derivative Imidazole Methylpyridine Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Pyridine Sulfinyl compound Sulfinylbenzimidazole Sulfoxide Aromatic heteropolycyclic compounds benzimidazoles pyridines sulfoxide Detected and Not Quantified Rabeprazole Action Pathway SMP0000229 Rabeprazole Metabolism Pathway SMP0000616 Rabeprazole Antacid Action Pathway SMP0123294 Rabeprazole Drug Metabolism Action Pathway SMP0143550 logp 2.09 logp 2.04 ALOGPS logs -3.03 ALOGPS solubility 3.36e-01 g/l ALOGPS logp 2.09 ChemAxon pka_strongest_acidic 9.35 ChemAxon pka_strongest_basic 4.24 ChemAxon iupac 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole ChemAxon average_mass 359.443 ChemAxon mono_mass 359.130362243 ChemAxon smiles COCCCOC1=C(C)C(CS(=O)C2=NC3=CC=CC=C3N2)=NC=C1 ChemAxon formula C18H21N3O3S ChemAxon inchi InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21) ChemAxon inchikey YREYEVIYCVEVJK-UHFFFAOYSA-N ChemAxon polar_surface_area 77.1 ChemAxon refractivity 98.07 ChemAxon polarizability 39.64 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf81fe2e0> DB01129 5029 4853 BE0000349