1.0 2016-06-03 11:02:13 UTC 2026-08-20 03:37:49 UTC benzydamine SmallMolecule Benzydamine is an organic compound with the chemical formula C19H23N3O and an average molecular weight of 309.41 g/mol. It belongs to the indazoles, a subclass of benzopyrazoles within the organic compounds. In terms of its biological activity, the compound acts as an inhibitor of two protein targets: Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). The substance is found in or released from 12 recorded sources across various sectors. Within healthcare, pharmaceuticals, and veterinary products, it is utilized in throat preparations, gynecologicals, stomatological preparations, antiinflammatory and antirheumatic products, and topical products for joint and muscular pain. Its presence is also noted in household cleaning and consumer products, including perfumes within detergents and soaps, soap detergents, tobacco product cases, cigar cigarettes, and non-electric simulated smoking devices. Additionally, it is associated with electrical and electronic equipment, specifically radio transmission systems and electrically stimulated smoking devices. Recorded exposure routes for benzydamine include dental, buccal, and oral pathways. C19H23N3O 309.413 309.184112373 {3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine tantum 642-72-8 CN(C)CCCOC1=NN(CC2=CC=CC=C2)C2=CC=CC=C12 InChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3 CNBGNNVCVSKAQZ-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzopyrazoles Indazoles Indazoles Alkyl aryl ethers Azacyclic compounds Benzene and substituted derivatives Heteroaromatic compounds Hydrocarbon derivatives Organopnictogen compounds Pyrazoles Trialkylamines Alkyl aryl ether Amine Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Benzopyrazole Ether Heteroaromatic compound Hydrocarbon derivative Indazole Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Pyrazole Tertiary aliphatic amine Tertiary amine Aromatic heteropolycyclic compounds Detected and Not Quantified Benzydamine Drug Metabolism Action Pathway SMP0144296 logp 3.66 logp 3.78 ALOGPS logs -3.80 ALOGPS solubility 4.91e-02 g/l ALOGPS logp 3.66 ChemAxon pka_strongest_basic 9.26 ChemAxon iupac {3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine ChemAxon average_mass 309.413 ChemAxon mono_mass 309.184112373 ChemAxon smiles CN(C)CCCOC1=NN(CC2=CC=CC=C2)C2=CC=CC=C12 ChemAxon formula C19H23N3O ChemAxon inchi InChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3 ChemAxon inchikey CNBGNNVCVSKAQZ-UHFFFAOYSA-N ChemAxon polar_surface_area 30.29 ChemAxon refractivity 105.56 ChemAxon polarizability 35.62 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 3 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226fb7c60> DB09084 12555 12036 BE0000017 BE0000262