1.0 2016-06-03 11:26:29 UTC 2026-08-20 03:52:06 UTC Profenamine SmallMolecule Profenamine is an organic compound with the chemical formula C19H24N2S and an average molecular weight of 312.47 g/mol. Profenamine belongs to the phenothiazines, a subclass of benzothiazines within the organic compounds. This compound is associated with 14 recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is used as an anticholinergic agent. It is also found in food preservation for food, food processing, and cookware. Other sources include non-electric simulated smoking devices used in household cleaning and consumer products, as well as electrical and electronic equipment, including antennas, auxiliary devices, electric switches, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. The recorded route of exposure for this compound is oral. At the molecular level, profenamine interacts with four recorded protein targets. It acts as an antagonist or modulator of the histamine H1 receptor (HRH1), the muscarinic acetylcholine receptor M1 (CHRM1), the muscarinic acetylcholine receptor M2 (CHRM2), and the glutamate receptor ionotropic, NMDA 3A (GRIN3A). C19H24N2S 312.472 312.166019468 diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine ethopropazine 522-00-9 CCN(CC)C(C)CN1C2=CC=CC=C2SC2=CC=CC=C12 InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 CDOZDBSBBXSXLB-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzothiazines Phenothiazines Phenothiazines 1,4-thiazines Alkyldiarylamines Azacyclic compounds Benzenoids Diarylthioethers Hydrocarbon derivatives Organopnictogen compounds Trialkylamines Alkyldiarylamine Amine Aromatic heteropolycyclic compound Aryl thioether Azacycle Benzenoid Diarylthioether Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Para-thiazine Phenothiazine Tertiary aliphatic amine Tertiary aliphatic/aromatic amine Tertiary amine Thioether Aromatic heteropolycyclic compounds phenothiazines tertiary amino compound Detected and Not Quantified Profenamine Action Pathway SMP0126229 Ethopropazine Drug Metabolism Pathway SMP0145318 logp 5 logp 5.75 ALOGPS logs -4.78 ALOGPS solubility 5.24e-03 g/l ALOGPS logp 5 ChemAxon pka_strongest_basic 9.6 ChemAxon iupac diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine ChemAxon average_mass 312.472 ChemAxon mono_mass 312.166019468 ChemAxon smiles CCN(CC)C(C)CN1C2=CC=CC=C2SC2=CC=CC=C12 ChemAxon formula C19H24N2S ChemAxon inchi InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 ChemAxon inchikey CDOZDBSBBXSXLB-UHFFFAOYSA-N ChemAxon polar_surface_area 6.48 ChemAxon refractivity 98 ChemAxon polarizability 36.34 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72443e0d38> DB00392 3290 3174 BE0000641 BE0000092 BE0000560 BE0000442