<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-03-26 19:40:59 UTC</creation_date>
  <update_date>2026-05-14 18:26:20 UTC</update_date>
  <accession/>
  <common_name>Triptorelin</common_name>
  <class>SmallMolecule</class>
  <description>Triptorelin is a compound with the chemical formula C64H82N18O13. Triptorelin belongs to the polypeptides, a class of organic polymers within the organic compounds. With an average molecular weight of 1,311 g/mol, Triptorelin is a heavy molecule.

As a pharmacological agent, Triptorelin acts as an agonist of the Gonadotropin-releasing hormone receptor (GNRHR). The compound is found in or released from healthcare, pharmaceuticals &amp; veterinary products (specifically hormones and related agents) and electrical &amp; electronic equipment (antennas). Recorded exposure routes for this compound include subcutaneous and intramuscular administration.</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>5-Oxoprolylhistidyltryptophylseryltyrosyltryptophylleucylarginylprolylglycinamide</synonym>
    <synonym>Glycinamide, 5-oxoprolylhistidyltryptophylseryltyrosyltryptophylleucylarginylprolyl-</synonym>
    <synonym>N-(2-amino-2-oxoethyl)-1-((5-oxopyrrolidine-2-carbonyl)histidyltryptophylseryltyrosyltryptophylleucylarginyl)pyrrolidine-2-carboxamide</synonym>
    <synonym>Triptorelin</synonym>
    <synonym>Triptorelin acetate</synonym>
    <synonym>Triptorelin pamoate</synonym>
  </synonyms>
  <chemical_formula>C64H82N18O13</chemical_formula>
  <average_molecular_weight>1311.473</average_molecular_weight>
  <monisotopic_moleculate_weight>1310.630875</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>57773-63-4</cas_registry_number>
  <smiles>CC(C)C[C@H](NC(=O)[C@@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)NCC(N)=O</smiles>
  <inchi>InChI=1S/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)</inchi>
  <inchikey>VXKHXGOKWPXY-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Triptorelin Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0144157</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-3.6</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>1311.473</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>1310.630875</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CC(C)C[C@H](NC(=O)[C@@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)NCC(N)=O</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C64H82N18O13</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>VXKHXGOKWPXY-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72442fa018&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB06825</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>25077179</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>11380138</chemspider_id>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
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  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
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    <target>
      <target_id>BE0000203</target_id>
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  </targets>
</compound>
