<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-03-26 23:46:17 UTC</creation_date>
  <update_date>2026-08-24 13:34:25 UTC</update_date>
  <accession/>
  <common_name>Azobisisobutyronitrile</common_name>
  <class>SmallMolecule</class>
  <description>Azobisisobutyronitrile is an organic nitrogen compound with the formula C8H12N4 and an average molecular weight of 164.21 g/mol. Azobisisobutyronitrile belongs to the azo compounds, a subclass of organonitrogen compounds within the organic compounds.

The compound is found in or released from 53 recorded sources across multiple sectors. Within electrical and electronic equipment, it is associated with antennas, amplifiers, communication cables or conductors, cores yokes or armatures, and conductors or conductive bodies characterised by the conductive materials, among 16 others. In the food, food processing and cookware sector, it is linked to food contact materials, food preservation, the preparation of wine or sparkling wine, fermentation processes for beer, and processing fish, as well as one additional source. Household cleaning and consumer product sources include soap detergents, bleaching agents, tobacco smoke filters, perfumes within detergents and soaps, and cigar cigarettes.

Environmental presence is noted in aquatic systems and sediments, specifically in freshwater, seawater, groundwater, and surface water. It is also detected in drinking water and water supply sources, including tap water, bottled water, desalinated water, and drinking water. Additionally, it is found in wastewater, sanitation and biosolids, including unspecified wastewater, mine wastewater, industrial wastewater, and wastewater treatment effluent, along with five more sectors. Recorded routes of exposure for this compound include oral, inhalation, and touch.</description>
  <categories/>
  <types>
    <type>PMT</type>
  </types>
  <synonyms>
    <synonym>.alpha.,.alpha.'-Azobis(isobutylonitrile)</synonym>
    <synonym>.alpha.,.alpha.'-Azobis[isobutyronitrile]</synonym>
    <synonym>.alpha.,.alpha.'-Azodi(isobutyronitrile)</synonym>
    <synonym>.alpha.,.alpha.'-Azodiisobutyric acid dinitrile</synonym>
    <synonym>.alpha.,.alpha.'-Azodiisobutyronitrile</synonym>
    <synonym>.alpha.,.alpha.'-Azodisobutyric acid dinitrile</synonym>
    <synonym>.alpha.,.alpha.-Azobisisobutyronitrile</synonym>
    <synonym>2,2'-(1,2-Diazenediyl)bis(2-methylpropanenitrile)</synonym>
    <synonym>2,2'-Azobis(2-methylpropionitrile)</synonym>
    <synonym>2,2'-Azobis-(2-methylpropanenitrile)</synonym>
    <synonym>2,2'-azobis[2-methyl-]-propanenitrile</synonym>
    <synonym>2,2'-Azobis[2-methylpropionitrile]</synonym>
    <synonym>2,2'-Azobis[isobutyronitrile]</synonym>
    <synonym>2,2'-AZODI(ISOBUTYRONITRILE)</synonym>
    <synonym>2,2'-Diazene-1,2-diylbis(2-methylpropanenitrile)</synonym>
    <synonym>2,2'-Dicyano-2,2'-azopropane</synonym>
    <synonym>2,2'-Dimethyl-2,2'-azodipropionitrile</synonym>
    <synonym>2,2'-Dimethyl-2,2'-azodipropiononitrile</synonym>
    <synonym>2,2-Azodiisobutyronitrile</synonym>
    <synonym>201-132-3</synonym>
    <synonym>Aceto AZIB</synonym>
    <synonym>AIBN</synonym>
    <synonym>Aivn</synonym>
    <synonym>Alpha,alpha'-azo-di-iso-butyronitrile</synonym>
    <synonym>Azdh</synonym>
    <synonym>Azobisisobutylonitrile</synonym>
    <synonym>Azobis[isobutyronitrile]</synonym>
    <synonym>Azodi(isobutyronitrile)</synonym>
    <synonym>Azodiisobutyrodinitrile</synonym>
    <synonym>Genitron AZDN</synonym>
    <synonym>Genitron AZDN-FF</synonym>
    <synonym>N,N'-Bis(2-cyano-2-propyl)diazene</synonym>
    <synonym>Poly-Zole AZDN</synonym>
    <synonym>Porofor 57</synonym>
    <synonym>Porofor N</synonym>
    <synonym>Porophor N</synonym>
    <synonym>Propanenitrile, 2,2'-(1,2-diazenediyl)bis(2-methyl-</synonym>
    <synonym>Propanenitrile, 2,2'-(1,2-diazenediyl)bis[2-methyl-</synonym>
    <synonym>Propionitrile, 2,2'-azobis[2-methyl-</synonym>
    <synonym>V-60</synonym>
    <synonym>VAZO</synonym>
    <synonym>VAZO 64</synonym>
  </synonyms>
  <chemical_formula>C8H12N4</chemical_formula>
  <average_molecular_weight>164.212</average_molecular_weight>
  <monisotopic_moleculate_weight>164.106196</monisotopic_moleculate_weight>
  <iupac_name>2-[(E)-2-(1-cyano-1-methylethyl)diazen-1-yl]-2-methylpropanenitrile</iupac_name>
  <traditional_iupac>azobisisobutyronitrile</traditional_iupac>
  <cas_registry_number>78-67-1;34241-39-9;161755-85-7;39322-24-2;58449-80-2;67035-64-7;76012-28-7;80748-81-8;95210-41-6</cas_registry_number>
  <smiles>CC(C)(N=NC(C)(C)C#N)C#N</smiles>
  <inchi>InChI=1S/C8H12N4/c1-7(2,5-9)11-12-8(3,4)6-10/h1-4H3</inchi>
  <inchikey>OZAIFHULBGXAKX-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Organic compounds</kingdom>
    <super_class>Organic nitrogen compounds</super_class>
    <class>Organonitrogen compounds</class>
    <sub_class>Azo compounds</sub_class>
    <direct_parent>Azo compounds</direct_parent>
    <alternate_parents>
      <alternative_parent>Hydrocarbon derivatives</alternative_parent>
      <alternative_parent>Nitriles</alternative_parent>
      <alternative_parent>Organopnictogen compounds</alternative_parent>
      <alternative_parent>Propargyl-type 1,3-dipolar organic compounds</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Aliphatic acyclic compound</substituent>
      <substituent>Azo compound</substituent>
      <substituent>Carbonitrile</substituent>
      <substituent>Hydrocarbon derivative</substituent>
      <substituent>Nitrile</substituent>
      <substituent>Organic 1,3-dipolar compound</substituent>
      <substituent>Organopnictogen compound</substituent>
      <substituent>Propargyl-type 1,3-dipolar organic compound</substituent>
    </substituents>
    <molecular_framework>Aliphatic acyclic compounds</molecular_framework>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>1.3</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>2.43</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logs</kind>
      <value>-2.84</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>solubility</kind>
      <value>2.40e-01 g/l</value>
      <source>ALOGPS</source>
    </property>
    <property>
      <kind>logp</kind>
      <value>1.27</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_basic</kind>
      <value>-6.3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>2-[(E)-2-(1-cyano-1-methylethyl)diazen-1-yl]-2-methylpropanenitrile</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>164.212</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>164.106196</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CC(C)(N=NC(C)(C)C#N)C#N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C8H12N4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C8H12N4/c1-7(2,5-9)11-12-8(3,4)6-10/h1-4H3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>OZAIFHULBGXAKX-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>72.3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>45.34</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>17.61</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baec288f0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id/>
  <hmdb_id/>
  <pubchem_compound_id>6547</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>6299</chemspider_id>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
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  <wikipidia/>
  <general_references/>
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  </targets>
</compound>
