1.0 2026-03-31 20:19:58 UTC 2026-05-14 18:07:12 UTC Antibiotic G 418 SmallMolecule Antibiotic G 418 is an organic compound with the formula C20H40N4O10 and an average molecular weight of 496.56 g/mol. Antibiotic G 418 belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. This compound is found in or released from three recorded sources: healthcare, pharmaceuticals & veterinary products (antibiotics), electrical & electronic equipment (antennas), and food, food processing & cookware (preparation of wine or sparkling wine). Recorded exposure routes include inhalation and oral intake. In terms of biological activity, Antibiotic G 418 acts as an inhibitor of the protein target ornithine decarboxylase (ODC1). (1S,2S,3R,4S,6R)-4,6-Diamino-3-({(5R)-2-amino-2-deoxy-5-[(1R)-1-hydroxyethyl]-alpha-D-xylopyranosyl}oxy)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside (1S,2S,3R,4S,6R)-4,6-Diamino-3-{[(5R)-2-amino-2-deoxy-5-(1-hydroxyethyl)-alpha-D-xylopyranosyl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside (2R,3S,4R,5R,6S)-5-amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-2-(1-hydroxyethyl)oxane-3,4-diol (2R,3S,4R,5R,6S)-5-AMINO-6-{[(1R,2S,3S,4R,6S)-4,6-DIAMINO-3-{[(2R,3R,4R,5R)-3,5-DIHYDROXY-5-METHYL-4-(METHYLAMINO)OXAN-2-YL]OXY}-2-HYDROXYCYCLOHEXYL]OXY}-2-[(1R)-1-HYDROXYETHYL]OXANE-3,4-DIOL (3s,5r,10s,13r,14r,17r)-17-(1,5-dimethylhex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-3-ol 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE A08F5XTI6G alpha-D-gluco-Heptopyranoside, (1R,2S,3S,4R,6S)-4,6-diamino-3-[[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy]-2-hydroxycyclohexyl 2-amino-2,7-dideoxy- antibiotic G 418 antibiotic G-418 Antibiotic G418 C20H40N4O10 D-glycero-alpha-D-gluco-Heptopyranoside, (1R,2S,3S,4R,6S)-4,6-diamino-3-[[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy]-2-hydroxycyclohexyl 2-amino-2,7-dideoxy- D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))- G 418 sulfate G-418 G418 G418 disulfate G418 Disulfate (50 mg/ml) Geneticin GET O-2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-D-streptamine UNII-A08F5XTI6G UNII:A08F5XTI6G C20H40N4O10 496.558 496.274444 49863-47-0;49662-03-5;83855-92-9 CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O InChI=1S/C20H40N4O10/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19/h6-19,24-30H,4-5,21-23H2,1-3H3/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+/m1/s1 BRZYSWJRSDMWLG-DJWUNRQOSA-N Detected and Not Quantified logp -5.3 average_mass 496.558 ChemAxon mono_mass 496.274444 ChemAxon smiles CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O ChemAxon formula C20H40N4O10 ChemAxon inchi InChI=1S/C20H40N4O10/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19/h6-19,24-30H,4-5,21-23H2,1-3H3/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+/m1/s1 ChemAxon inchikey BRZYSWJRSDMWLG-DJWUNRQOSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226df3528> DB04263 123865 110402 BE0000404