1.0 2026-03-31 21:02:23 UTC 2026-05-14 17:49:57 UTC Ubenimex SmallMolecule Ubenimex is an organic compound with the formula C16H24N2O4 and an average molecular weight of 308.38 g/mol. Ubenimex belongs to the hybrid peptides, a subclass of peptidomimetics within the organic compounds. This substance is found in or released from healthcare, pharmaceuticals & veterinary products, specifically antibiotics, with recorded exposure routes including oral and inhalation. In terms of biological activity, Ubenimex acts on two recorded protein targets. It functions as an inhibitor of Bacterial leucyl aminopeptidase and targets Leukotriene A-4 hydrolase (LTA4H). (-)-N-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl)-L-leucine (2S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoylamino)-4-methylpentanoic acid (2S)-2-[[(2S,3R)-3-azaniumyl-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoate (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl-L-leucine (3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoic acid (S-(R*,S*))-N-(3-Amino-2-hydroxy-4-phenylbutyroyl)-L-leucine ([2S,3R]-3-Amino-2-hydroxy-4-phenylbutanoyl)-L-leucine 2-(3-Amino-2-hydroxy-4-phenyl-butyrylamino)-4-methyl-pentanoic acid 261-529-2 3-(R)-Amino-2-(S)-hydroxy-4-phenylbutanoyl-(S)-leucine BEK BES Bestatin Bestatin free base Bestatin_x000D_ I0J33N5627 L-Leucine, N-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-, (S-(R*,S*))- L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]- N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine OH2915000 QA-1889 Ubenimex Ubenimex (Bestatin) Ubenimex [INN:JAN] Ubenimex | Ubenimex(Bestatin) Ubenimex, Bestatin Ubestatin UNII:I0J33N5627 [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine [58970-76-6] C16H24N2O4 308.378 308.173607 (2S)-2-{[(2S,3R)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-4-methylpentanoic acid (2S)-2-{[(2S,3R)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-4-methylpentanoic acid 58970-76-6 CC(C)C[C@@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(O)=O InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 VGGGPCQERPFHOB-RDBSUJKOSA-N Organic compounds Organic acids and derivatives Peptidomimetics Hybrid peptides Hybrid peptides Amino acids Amphetamines and derivatives Aralkylamines Beta amino acids and derivatives Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Leucine and derivatives Monoalkylamines Monocarboxylic acids and derivatives Monosaccharides N-acyl amines N-acyl-L-alpha-amino acids Organic oxides Organopnictogen compounds Secondary alcohols Secondary carboxylic acid amides Alcohol Alpha-amino acid or derivatives Amine Amino acid Amino acid or derivatives Amphetamine or derivatives Aralkylamine Aromatic homomonocyclic compound Benzenoid Beta amino acid or derivatives Carbonyl group Carboxamide group Carboxylic acid Carboxylic acid derivative Fatty acyl Fatty amide Hybrid peptide Hydrocarbon derivative Leucine or derivatives Monocarboxylic acid or derivatives Monocyclic benzene moiety Monosaccharide N-acyl-alpha amino acid or derivatives N-acyl-alpha-amino acid N-acyl-amine N-acyl-l-alpha-amino acid Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Secondary alcohol Secondary carboxylic acid amide Aromatic homomonocyclic compounds Detected and Not Quantified logp -1.1 logp -1.66 ALOGPS logs -2.56 ALOGPS solubility 8.41e-01 g/l ALOGPS logp -0.46 ChemAxon pka_strongest_acidic 3.77 ChemAxon pka_strongest_basic 9.54 ChemAxon iupac (2S)-2-{[(2S,3R)-3-amino-1,2-dihydroxy-4-phenylbutylidene]amino}-4-methylpentanoic acid ChemAxon average_mass 308.378 ChemAxon mono_mass 308.173607 ChemAxon smiles CC(C)C[C@@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(O)=O ChemAxon formula C16H24N2O4 ChemAxon inchi InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 ChemAxon inchikey VGGGPCQERPFHOB-RDBSUJKOSA-N ChemAxon polar_surface_area 116.14 ChemAxon refractivity 82.57 ChemAxon polarizability 32.97 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7221bcdca8> DB03424 72172 65145 BE0001395 BE0001680