<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-02 23:12:41 UTC</creation_date>
  <update_date>2026-05-20 18:23:08 UTC</update_date>
  <accession/>
  <common_name>Diosgenin</common_name>
  <class>SmallMolecule</class>
  <description>Diosgenin (C27H42O3) is a compound that belongs to the triterpenoids, a subclass of prenol lipids within the organic compounds. Biologically, it functions as an antioxidant, while its industrial applications include use as a softener and conditioner (PMC3867356).

The compound is found in or released from 17 recorded sources across several sectors. These include electrical and electronic equipment, such as batteries, capacitors, cell phones, printed circuit boards, and wires and cables. In the food, food processing, and cookware sector, it is associated with food packaging and the preparation of vinegar and wort. It is also found in lubricants within the energy, oil, and gas sector, medical devices in the healthcare, pharmaceuticals, and veterinary products sector, and synthetic textiles, carpets, and rugs within the textiles, leather, and furnishings sector. Additionally, it is present in drinking water and water supply, among two other sectors. Recorded exposure routes for the compound include oral, inhalation, and touch.

Regarding health effects, diosgenin is used as a treatment for cancer (PMC10125993). It is also used in the treatment of asthma, leukemia, arthritis, and rheumatoid arthritis (PMC11592201).</description>
  <categories/>
  <types>
    <type>PFAS</type>
    <type>Phytotoxin</type>
  </types>
  <synonyms>
    <synonym>(20R,25R)-spirost-5-en-3?-ol</synonym>
    <synonym>(20R,25R)-Spirost-5-en-3beta-ol</synonym>
    <synonym>(25R)-5-Spirosten-3ÃƒÆ’Ã‚Å½Ãƒâ€šÃ‚Â²-ol</synonym>
    <synonym>(25R)-5-Spirosten-3beta-ol</synonym>
    <synonym>(25R)-Spirost-5-en-3b-ol</synonym>
    <synonym>(25R)-spirost-5-en-3beta-ol</synonym>
    <synonym>(2S,4aR,4bS,5'R,6aS,6bR,7S,8R,9aS,10aS,10bS)-4a,5',6a,7-TÃƒÆ’Ã‚Â©tramÃƒÆ’Ã‚Â©thyl-1,2,3,3',4,4',4a,4b,5,5',6,6',6a,6b,7,9a,10,10a,10b,11-icosahydrospiro[naphto[2',1':4,5]indÃƒÆ’Ã‚Â©no[2,1-b]furane-8,2'-pyran]-2-ol</synonym>
    <synonym>(2S,4aR,4bS,5'R,6aS,6bR,7S,8R,9aS,10aS,10bS)-4a,5',6a,7-Tetramethyl-1,2,3,3',4,4',4a,4b,5,5',6,6',6a,6b,7,9a,10,10a,10b,11-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-8,2'-pyran]-2-ol</synonym>
    <synonym>(3?,25R)-spirost-5-en-3-ol</synonym>
    <synonym>(3b,25R)-Spirost-5-en-3-ol</synonym>
    <synonym>(3bÃƒÆ’Ã‚Âªta,25R)-Spirost-5-ÃƒÆ’Ã‚Â¨n-3-ol</synonym>
    <synonym>(3beta,25R)-Spirost-5-en-3-ol</synonym>
    <synonym>(4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol</synonym>
    <synonym>(7S,8S,10S,13S,15S,18S,22S,3R,12R,14R,19R)-3,13,15,19-tetramethyl-11-oxaspiro[ 2H-3,4,5,6-tetrahydropyran-6,6'-pentacyclo[10.8.0.0.0.0]icosa ne]-24-en-22-ol</synonym>
    <synonym>(7S,8S,10S,13S,15S,18S,22S,3R,12R,14R,19R)-3,13,15,19-tetramethyl-11-oxaspiro[2H-3,4,5,6-tetrahydropyran-6,6'-pentacyclo[10.8.0.0.0.0]icosane]-24-en-22-ol</synonym>
    <synonym>3$b-Hydroxy-5-spirostene</synonym>
    <synonym>3ÃƒÆ’Ã‚Å½Ãƒâ€šÃ‚Â²-Hydroxy-5-spirostene</synonym>
    <synonym>3BETA-HYDROXY-5-SPIROSTENE</synonym>
    <synonym>4/9/512</synonym>
    <synonym>4a,5',6a,7-tetramethyl-(4aR,4bS,5'R,6aS,6bR,7S,8'R,9aS,10aS,10bR)-spiro[2,3,4,4a,4b,5,6,6a,6b,7,8,9a,10,10a,10b,11-hexadecahydro-1H-naphtho[2',1':4,5]indeno[2,1-b]furan-8,2'-(dihydro-4'H-pyran)]-2-ol</synonym>
    <synonym>9/4/512</synonym>
    <synonym>94582</synonym>
    <synonym>DHA</synonym>
    <synonym>Diosgenin</synonym>
    <synonym>Diosgeninwas TCI D1474</synonym>
    <synonym>MFCD00016887</synonym>
    <synonym>Nitogenin</synonym>
    <synonym>QA-9446</synonym>
    <synonym>Spirost-5-en-3-beta-ol, (25R)-</synonym>
    <synonym>Spirost-5-en-3-ol, (3.beta.,25R)-</synonym>
    <synonym>Spirost-5-en-3-ol, (3b,25R)-</synonym>
    <synonym>Spirost-5-en-3-ol, (3beta,25R)-</synonym>
    <synonym>Spirost-5-en-3-ol, (3beta,25S)-</synonym>
    <synonym>Spirost-5-en-3-ol,(3b,25R)-</synonym>
    <synonym>Spirost-5-en-3.beta.-ol, (25R)-</synonym>
    <synonym>UNII-K49P2K8WLX</synonym>
    <synonym>UNII:K49P2K8WLX</synonym>
    <synonym>WH1450000</synonym>
    <synonym>[512-04-9]</synonym>
  </synonyms>
  <chemical_formula>C27H42O3</chemical_formula>
  <average_molecular_weight/>
  <monisotopic_moleculate_weight>414.313395</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>512-04-9</cas_registry_number>
  <smiles/>
  <inchi>InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1</inchi>
  <inchikey>WQLVFSAGQJTQCK-VKROHFNGSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties/>
  <predicted_properties>
    <property>
      <kind>mono_mass</kind>
      <value>414.313395</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C27H42O3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>WQLVFSAGQJTQCK-VKROHFNGSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf8654380&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id/>
  <hmdb_id/>
  <pubchem_compound_id>99474</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>89870</chemspider_id>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
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  </targets>
</compound>
