<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-03 01:20:46 UTC</creation_date>
  <update_date>2026-08-20 04:19:44 UTC</update_date>
  <accession/>
  <common_name>Phosphonic acid, [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-, diethyl ester</common_name>
  <class>SmallMolecule</class>
  <description>Phosphonic acid, [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-, diethyl ester belongs to the phenylpropanes, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula $\text{C}_{19}\text{H}_{33}\text{O}_4\text{P}_1$ and an average molecular weight of 356.44 g/mol.

In industrial applications, the compound is utilized as an antioxidant. It has been identified in nine recorded sources. These include various types of electrical and electronic equipment, such as antennas, coils, communication cables or conductors, discharge lamps, and electric switches, among two others. Additionally, the substance is found in household items, specifically credit card holders, and is associated with food, food processing and cookware, where it is used in the processing of meats.</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>2,6-ditert-butyl-4-(diethoxyphosphorylmethyl)phenol</synonym>
    <synonym>213-551-9</synonym>
    <synonym>Antioxidant 1222</synonym>
    <synonym>Diethyl ((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methyl)phosphonate</synonym>
    <synonym>diethyl (3,5-di-tert-butyl-4-hydroxybenzyl)phosphonate</synonym>
    <synonym>DIETHYL (3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)METHYLPHOSPHOTE</synonym>
    <synonym>Diethyl 3,5-di-tert-butyl-4-hydroxybenzyl phosphate</synonym>
    <synonym>Diethyl 3,5-Di-tert-butyl-4-hydroxybenzylphosphonate</synonym>
    <synonym>Diethyl [4-hydroxy-3,5-bis(2-methyl-2-propanyl)benzyl]phosphonate</synonym>
    <synonym>diethyl [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]phosphonate</synonym>
    <synonym>Diethyl [[3,5-dis(1,1-dimethylethyl)-4-OHphenyl]methyl]phosphonate</synonym>
    <synonym>Diethyl(3,5-di-tert-butyl-4-OHphenyl)methanephosphonate</synonym>
    <synonym>diethyl3,5-di-tert-butyl-4-hydroxybenzylphosphate</synonym>
    <synonym>Diethyl[4-OH-3,5-bis(2-methyl-2-propanyl)benzyl]phosphonate</synonym>
    <synonym>EINECS 213-551-9</synonym>
    <synonym>Irganox 1222</synonym>
    <synonym>Monoethyl 3,5-Di-tert-butyl-4-hydroxybenzylphosphonate</synonym>
    <synonym>Phosphonic acid, ((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methyl)-, diethyl ester</synonym>
    <synonym>Phosphonic acid, P-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-, diethyl ester</synonym>
    <synonym>Phosphonic acid, [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-, diethyl ester</synonym>
    <synonym>Phosphonic acid,P-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-, diethyl ester</synonym>
    <synonym>phosphoric acid (3,5-ditert-butyl-4-hydroxyphenyl)methyl diethyl ester</synonym>
    <synonym>UNII-V6MOU97T5J</synonym>
    <synonym>UNII:V6MOU97T5J</synonym>
    <synonym>[976-56-7]</synonym>
    <synonym>{[3,5-bis(tert-butyl)-4-hydroxyphenyl]methyl}diethoxyphosphino-1-one</synonym>
  </synonyms>
  <chemical_formula>C19H33O4P1</chemical_formula>
  <average_molecular_weight>356.443</average_molecular_weight>
  <monisotopic_moleculate_weight>356.211646</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>976-56-7</cas_registry_number>
  <smiles>CCOP(=O)(CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)OCC</smiles>
  <inchi>InChI=1S/C19H33O4P/c1-9-22-24(21,23-10-2)13-14-11-15(18(3,4)5)17(20)16(12-14)19(6,7)8/h11-12,20H,9-10,13H2,1-8H3</inchi>
  <inchikey>GJDRKHHGPHLVNI-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Organic compounds</kingdom>
    <super_class>Benzenoids</super_class>
    <class>Benzene and substituted derivatives</class>
    <sub_class>Phenylpropanes</sub_class>
    <direct_parent>Phenylpropanes</direct_parent>
    <alternate_parents>
      <alternative_parent>Dialkyl alkylphosphonates</alternative_parent>
      <alternative_parent>Hydrocarbon derivatives</alternative_parent>
      <alternative_parent>Organic oxides</alternative_parent>
      <alternative_parent>Organooxygen compounds</alternative_parent>
      <alternative_parent>Organophosphorus compounds</alternative_parent>
      <alternative_parent>Organopnictogen compounds</alternative_parent>
      <alternative_parent>Phenols</alternative_parent>
      <alternative_parent>Phosphonic acid esters</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Aromatic homomonocyclic compound</substituent>
      <substituent>Dialkyl alkylphosphonate</substituent>
      <substituent>Hydrocarbon derivative</substituent>
      <substituent>Organic oxide</substituent>
      <substituent>Organic oxygen compound</substituent>
      <substituent>Organooxygen compound</substituent>
      <substituent>Organophosphonic acid derivative</substituent>
      <substituent>Organophosphorus compound</substituent>
      <substituent>Organopnictogen compound</substituent>
      <substituent>Phenol</substituent>
      <substituent>Phenylpropane</substituent>
      <substituent>Phosphonic acid diester</substituent>
      <substituent>Phosphonic acid ester</substituent>
    </substituents>
    <molecular_framework>Aromatic homomonocyclic compounds</molecular_framework>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>4.7</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>356.443</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>356.211646</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CCOP(=O)(CC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)OCC</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C19H33O4P1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C19H33O4P/c1-9-22-24(21,23-10-2)13-14-11-15(18(3,4)5)17(20)16(12-14)19(6,7)8/h11-12,20H,9-10,13H2,1-8H3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>GJDRKHHGPHLVNI-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
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  <lethaldose/>
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  <use_source/>
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  <symptoms/>
  <treatment/>
  <drugbank_id/>
  <hmdb_id/>
  <pubchem_compound_id>70421</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>63600</chemspider_id>
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</compound>
