1.0 2026-04-04 00:12:12 UTC 2026-05-14 19:02:24 UTC Trimebutine SmallMolecule Trimebutine is an organic compound with the chemical formula C22H29N1O5 and an average molecular weight of 387.48 g/mol. Trimebutine belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. It is further classified as part of the benzenoids superclass. The compound is associated with healthcare, pharmaceuticals, and veterinary products, specifically serving as a drug for functional gastrointestinal disorders. Recorded exposure routes for this substance include oral, intravenous, and intramuscular administration. Trimebutine interacts with 26 recorded protein targets. It acts as an activator, agonist, antagonist, or inhibitor of the Mu-type opioid receptor (OPRM1), as well as the voltage-dependent L-type calcium channel subunit beta-4 (CACNB4), the voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A), and the voltage-dependent L-type calcium channel subunit alpha-1F (CACNA1F). Additionally, it targets 22 other proteins. (.+/-.)-2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate .beta.-(Dimethylamino)-.beta.-ethylphenethyl alcohol 3,4,5-trimethoxybenzoate (ester) 2'-Phenyl-2'-dimethylamino-N-but 2-(dimethylamino)-2-phenylbutyl (-)-3,4,5-trimethoxybenzoate 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate 2-(dimethylamino)-2-phenylbutyl 3,4,5-tris(methyloxy)benzoate 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoat 254-309-2 261-546-5 261-547-0 261-548-6 3,4,5-Trimethoxy-benzoic acid 2-dimethylamino-2-phenyl-butyl ester 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate salt 3,4,5-TRIMETHOXYBENZOIC ACID 2-[DIMETHYLAMINO]-2-PHENYLBUTYL ESTER 3,4,5-trimethoxybenzoic acid [2-(dimethylamino)-2-phenyl-butyl] ester 3,4,5-trimethoxybenzoic acid [2-(dimethylamino)-2-phenylbutyl] ester Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester BENZOIC ACID, 3,4,5-TRIMETHOXY-, 2-(DIMETHYLAMINO)-2-PHENYLBUTYL ESTER, (+-)- Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester, (.+/-.)- BENZOIC ACID, 3,4,5-TRIMETHOXY-, beta-(DIMETHYLAMINO)-beta-ETHYLPHENETHYL ESTER Benzoic acid,3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester beta-(Dimethylamino)-beta-ethylphenethyl alcohol 3,4,5-trimethoxybenzoate (ester) Cerekinon Debridat Digerent maleic acid Mebutin Polibutin QA-3510 QZ1OJ92E5R Spabucol Trimebutine Trimebutine base Trimebutine free base Trimebutine Maleate Trimebutine-d5 Trimedat UNII:QZ1OJ92E5R [1-ethyl-1-phenyl-2-(3,4,5-trimethoxybenzoyloxy)ethyl]dimethylammonium hydrogen maleate [2-(dimethylamino)-2-phenyl-butyl] 3,4,5-trimethoxybenzoate [2-(dimethylamino)-2-phenylbutyl] 3,4,5-trimethoxybenzoate [39133-31-8] [58997-88-9] C22H29N1O5 387.476 387.204573 39133-31-8 CCC(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)C1=CC=CC=C1 InChI=1S/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3/t22-/m1/s1 LORDFXWUHHSAQU-UHFFFAOY-N Detected and Not Quantified logp 4.11 average_mass 387.476 ChemAxon mono_mass 387.204573 ChemAxon smiles CCC(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)C1=CC=CC=C1 ChemAxon formula C22H29N1O5 ChemAxon inchi InChI=1S/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3/t22-/m1/s1 ChemAxon inchikey LORDFXWUHHSAQU-UHFFFAOY-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72a9b49100> DB09089 15008 BE0000770 BE0002356 BE0000356 BE0002357 BE0002358 BE0002359 BE0000303 BE0002354 BE0002355 BE0000430 BE0000415 BE0000553 BE0004422 BE0004424 BE0004425 BE0004426 BE0004423 BE0004427 BE0003196 BE0000483 BE0000864 BE0000012 BE0000092 BE0000560 BE0000045 BE0000405