<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-04 05:30:10 UTC</creation_date>
  <update_date>2026-08-20 05:57:34 UTC</update_date>
  <accession/>
  <common_name>Clebopride</common_name>
  <class>SmallMolecule</class>
  <description>Clebopride is an organic compound with the chemical formula C20H24Cl1N3O2 and an average molecular weight of 373.88 g/mol. Clebopride belongs to the benzylpiperidines, a subclass of piperidines within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds.

The compound is associated with 39 recorded sources across various sectors. In the category of electrical and electronic equipment, it is found in antennas, amplifiers, auxiliary devices, contacts, and conductors or conductive bodies characterised by the conductive materials. Within building and construction, it is released from ceilings, floors, fencing, ladders, and stairs and ramps. In the realm of food, food processing and cookware, it is linked to food preservation, the processing of meats, the processing of fish, the preparation of wort, and the preparation of vinegar. Additionally, it is found in household cleaning and consumer products, including soap detergents, tobacco product cases, pipe accessories, other smoking requisites, and non electric simulated smoking devices.

Regarding its biological activity, clebopride interacts with two recorded protein targets. It functions as an inhibitor of the D(2) dopamine receptor (DRD2) and also targets acetylcholinesterase (ACHE).</description>
  <categories/>
  <types/>
  <synonyms>
    <synonym>259-885-9</synonym>
    <synonym>4-amino-5-chloro-2-(methyloxy)-N-[1-(phenylmethyl)piperidin-4-yl]benzamide</synonym>
    <synonym>4-Amino-5-chloro-2-methoxy-N-(1-benzyl-4-piperidyl)benzamide</synonym>
    <synonym>4-Amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide</synonym>
    <synonym>4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidyl]benzamide</synonym>
    <synonym>4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)piperidin-4-yl]benzamide</synonym>
    <synonym>4-Amino-N-(1-benzyl-4-piperidinyl)-5-chloro-2-methoxybenzamide</synonym>
    <synonym>4-Amino-N-(1-benzyl-4-piperidyl)-5-chloro-o-anisamide</synonym>
    <synonym>4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide</synonym>
    <synonym>4-Amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide</synonym>
    <synonym>4-amino-N-[1-(benzyl)-4-piperidyl]-5-chloro-2-methoxy-benzamide</synonym>
    <synonym>5-22-08-00086</synonym>
    <synonym>Anti-Secretory Agent</synonym>
    <synonym>Benzamide, 4-amino-5-chloro-2-methoxy-N-(1-(phenylmethyl)-4-piperidinyl)-</synonym>
    <synonym>Benzamide, 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]-</synonym>
    <synonym>BPBio1_000593</synonym>
    <synonym>BSPBio_000539</synonym>
    <synonym>BSPBio_003597</synonym>
    <synonym>CAS-84370-95-6</synonym>
    <synonym>CHEMBL325109</synonym>
    <synonym>Cleboprida [INN-Spanish]</synonym>
    <synonym>Clebopride</synonym>
    <synonym>Clebopride (USAN)</synonym>
    <synonym>Clebopride Malate</synonym>
    <synonym>Clebopridum [INN-Latin]</synonym>
    <synonym>Cleboril (TN)</synonym>
    <synonym>EINECS 259-885-9</synonym>
    <synonym>N-(1'-Benzyl-4'-piperidyl)-2-methoxy-4-amino-5-chlorobenzamide</synonym>
    <synonym>Prestwick2_000380</synonym>
    <synonym>Prestwick3_000380</synonym>
    <synonym>Spectrum5_001571</synonym>
    <synonym>T6NTJ A1R&amp; DMVR DZ CG FO1</synonym>
    <synonym>UNII-I0A84520Y9</synonym>
    <synonym>UNII:I0A84520Y9</synonym>
    <synonym>[55905-53-8]</synonym>
  </synonyms>
  <chemical_formula>C20H24Cl1N3O2</chemical_formula>
  <average_molecular_weight>373.88</average_molecular_weight>
  <monisotopic_moleculate_weight>373.155705</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>55905-53-8</cas_registry_number>
  <smiles>COC1=C(C=C(Cl)C(N)=C1)C(=O)NC1CCN(CC2=CC=CC=C2)CC1</smiles>
  <inchi>InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)</inchi>
  <inchikey>BVPWJMCABCPUQY-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Organic compounds</kingdom>
    <super_class>Organoheterocyclic compounds</super_class>
    <class>Piperidines</class>
    <sub_class>Benzylpiperidines</sub_class>
    <direct_parent>N-benzylpiperidines</direct_parent>
    <alternate_parents>
      <alternative_parent>Alkyl aryl ethers</alternative_parent>
      <alternative_parent>Aminophenyl ethers</alternative_parent>
      <alternative_parent>Anisoles</alternative_parent>
      <alternative_parent>Aralkylamines</alternative_parent>
      <alternative_parent>Aryl chlorides</alternative_parent>
      <alternative_parent>Azacyclic compounds</alternative_parent>
      <alternative_parent>Benzylamines</alternative_parent>
      <alternative_parent>Carboximidic acids</alternative_parent>
      <alternative_parent>Chlorobenzenes</alternative_parent>
      <alternative_parent>Hydrocarbon derivatives</alternative_parent>
      <alternative_parent>Methoxyanilines</alternative_parent>
      <alternative_parent>Methoxybenzenes</alternative_parent>
      <alternative_parent>Organochlorides</alternative_parent>
      <alternative_parent>Organopnictogen compounds</alternative_parent>
      <alternative_parent>Phenoxy compounds</alternative_parent>
      <alternative_parent>Phenylmethylamines</alternative_parent>
      <alternative_parent>Primary amines</alternative_parent>
      <alternative_parent>Propargyl-type 1,3-dipolar organic compounds</alternative_parent>
      <alternative_parent>Trialkylamines</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Alkyl aryl ether</substituent>
      <substituent>Amine</substituent>
      <substituent>Aminophenyl ether</substituent>
      <substituent>Aniline or substituted anilines</substituent>
      <substituent>Anisole</substituent>
      <substituent>Aralkylamine</substituent>
      <substituent>Aromatic heteromonocyclic compound</substituent>
      <substituent>Aryl chloride</substituent>
      <substituent>Aryl halide</substituent>
      <substituent>Azacycle</substituent>
      <substituent>Benzenoid</substituent>
      <substituent>Benzylamine</substituent>
      <substituent>Carboximidic acid</substituent>
      <substituent>Carboximidic acid derivative</substituent>
      <substituent>Chlorobenzene</substituent>
      <substituent>Ether</substituent>
      <substituent>Halobenzene</substituent>
      <substituent>Hydrocarbon derivative</substituent>
      <substituent>Methoxyaniline</substituent>
      <substituent>Methoxybenzene</substituent>
      <substituent>Monocyclic benzene moiety</substituent>
      <substituent>N-benzylpiperidine</substituent>
      <substituent>Organic 1,3-dipolar compound</substituent>
      <substituent>Organic nitrogen compound</substituent>
      <substituent>Organic oxygen compound</substituent>
      <substituent>Organochloride</substituent>
      <substituent>Organohalogen compound</substituent>
      <substituent>Organonitrogen compound</substituent>
      <substituent>Organooxygen compound</substituent>
      <substituent>Organopnictogen compound</substituent>
      <substituent>Phenol ether</substituent>
      <substituent>Phenoxy compound</substituent>
      <substituent>Phenylmethylamine</substituent>
      <substituent>Primary amine</substituent>
      <substituent>Propargyl-type 1,3-dipolar organic compound</substituent>
      <substituent>Tertiary aliphatic amine</substituent>
      <substituent>Tertiary amine</substituent>
    </substituents>
    <molecular_framework>Aromatic heteromonocyclic compounds</molecular_framework>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>2.42</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>373.88</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>373.155705</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>COC1=C(C=C(Cl)C(N)=C1)C(=O)NC1CCN(CC2=CC=CC=C2)CC1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C20H24Cl1N3O2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>BVPWJMCABCPUQY-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72002549e0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB13511</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>2780</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id>4925598</chemspider_id>
  <kegg_id/>
  <uniprot_id/>
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  <chebi_id/>
  <biocyc_id/>
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  <wikipidia/>
  <general_references/>
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      <target_id>BE0000756</target_id>
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  </targets>
</compound>
