1.0 2026-04-04 14:04:06 UTC 2026-08-20 06:43:08 UTC Vernakalant SmallMolecule Vernakalant is an organic compound with the formula C20H31N1O4 and an average molecular weight of 349.47 g/mol. Vernakalant belongs to the tyrosols and derivatives, a subclass of phenols within the organic compounds. This compound is utilized within healthcare, pharmaceuticals, and veterinary products as a class I and III antiarrhythmic, with intravenous administration as the recorded route of exposure. Vernakalant acts on four recorded protein targets, serving as a blocker of the sodium channel protein type 5 subunit alpha (SCN5A), the potassium voltage-gated channel subfamily A member 5 (KCNA5), the A-type voltage-gated potassium channel KCND3, and the voltage-gated inwardly rectifying potassium channel KCNH2. (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol (3R)-1-{(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl}-3-pyrrolidinol (3R)-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl}pyrrolidin-3-ol (R)-1-((1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexyl)pyrrolidin-3-ol 3-Pyrrolidinol, 1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]-, (3R)- Brinavess Kynapid MFCD16038313 RSD 1235 RSD-1235 RSD1235 UNII-9G468C8B13 UNII:9G468C8B13 Vernakalant [794466-70-9] C20H31N1O4 349.471 349.225308 794466-70-9 COC1=C(OC)C=C(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)C=C1 InChI=1S/C20H31NO4/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21/h7-8,13,16-18,22H,3-6,9-12,14H2,1-2H3/t16-,17-,18-/m1/s1 VBHQKCBVWWUUKN-KZEPCWSA-N Detected and Not Quantified Vernakalant Drug Metabolism Action Pathway SMP0144017 logp 2.51 average_mass 349.471 ChemAxon mono_mass 349.225308 ChemAxon smiles COC1=C(OC)C=C(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)C=C1 ChemAxon formula C20H31N1O4 ChemAxon inchi InChI=1S/C20H31NO4/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21/h7-8,13,16-18,22H,3-6,9-12,14H2,1-2H3/t16-,17-,18-/m1/s1 ChemAxon inchikey VBHQKCBVWWUUKN-KZEPCWSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bae5ccbc8> DB06217 9930049 8105680 BE0000197 BE0004717 BE0003604 BE0000090