1.0 2026-04-04 18:11:13 UTC 2026-05-14 18:16:25 UTC Abiraterone SmallMolecule Abiraterone belongs to the androstane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound has the formula C24H31N1O1 and an average molecular weight of 349.52 g/mol. It is found in healthcare, pharmaceuticals, and veterinary products, specifically as an antineoplastic agent and a hormone antagonist and related agent. The recorded route of exposure for this compound is oral. At the molecular level, abiraterone acts as an inhibitor of the protein target Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1). Use of the compound is associated with several health effects, including edema (PMC9869701), hypokalemia (PMC9869701), and cognitive impairment (PMC9869701). Additionally, it is linked to hypertension (PMC9869701) and an increase in both hypertension (PMC9869701) and heart failure (PMC9869701). (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol 17-(3-Pyridinyl)androsta-5,16-dien-3-ol 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)- CB 7598,16-dien-3-ol,CB7598 C24H31N1O1 349.518 349.240565 154229-19-3 [H][C@@]12CC=C(C3=CN=CC=C3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3 GZOSMCIZMLWJML-UHFFFAOYSA-N Detected and Not Quantified Abiraterone Drug Metabolism Action Pathway SMP0143982 logp 3.97 average_mass 349.518 ChemAxon mono_mass 349.240565 ChemAxon smiles [H][C@@]12CC=C(C3=CN=CC=C3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C ChemAxon formula C24H31N1O1 ChemAxon inchi InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3 ChemAxon inchikey GZOSMCIZMLWJML-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72217ebc20> DB05812 132971 117349 BE0000344