1.0 2026-04-04 18:13:41 UTC 2026-05-14 19:02:15 UTC Umeclidinium SmallMolecule Umeclidinium is an organic compound with the formula C29H34N1O2 and an average molecular weight of 428.60 g/mol. Umeclidinium belongs to the diphenylmethanes, a subclass of benzene and substituted derivatives within the organic compounds. This compound is found in or released from two recorded sources: household cleaning and consumer products, specifically pipe accessories, and healthcare, pharmaceuticals and veterinary products, where it is used as a drug for obstructive airway diseases. Recorded exposure routes for the substance include oral and respiratory pathways. Regarding its biological activity, umeclidinium interacts with five recorded protein targets. It functions as an antagonist of the muscarinic acetylcholine receptors M1 (CHRM1), M2 (CHRM2), M3 (CHRM3), and M4 (CHRM4), in addition to one other protein. 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]- 1-[2-(Benzyloxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane di(phenyl)-[1-[2-(phenylmethoxy)ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]methanol di(phenyl)-[1-[2-(phenylmethoxy)ethyl]-4-quinuclidin-1-iumyl]methanol di(phenyl)-[1-[2-(phenylmethoxy)ethyl]quinuclidin-1-ium-4-yl]methanol GE2T1418SV Incruse Ellipta® Umeclidinium UNII-GE2T1418SV UNII:GE2T1418SV [1-[2-(benzyloxy)ethyl]quinuclidin-1-ium-4-yl]-di(phenyl)methanol C29H34N1O2 428.595 428.258954 869185-19-3 OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2 InChI=1S/C29H34NO2/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25/h1-15,31H,16-24H2/q+1 FVTWTVQXJTQP-UHFFFAOYSA-N Detected and Not Quantified Umeclidinium Drug Metabolism Action Pathway SMP0144289 logp 0.68 average_mass 428.595 ChemAxon mono_mass 428.258954 ChemAxon smiles OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2 ChemAxon formula C29H34N1O2 ChemAxon inchi InChI=1S/C29H34NO2/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25/h1-15,31H,16-24H2/q+1 ChemAxon inchikey FVTWTVQXJTQP-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72257ffb40> DB09076 11519070 9693858 BE0000092 BE0000560 BE0000045 BE0000405 BE0000247