1.0 2026-04-05 00:34:17 UTC 2026-05-14 19:48:19 UTC 17,21-Dihydroxy-16a-methylpregna-1,4,9(11)-triene-3,20-dione SmallMolecule 17,21-Dihydroxy-16a-methylpregna-1,4,9(11)-triene-3,20-dione belongs to the hydroxysteroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound has the chemical formula C22H28O4 and an average molecular weight of 356.46 g/mol. It is identified as a lipid-like molecule. The compound is found in or released from healthcare, pharmaceuticals, and veterinary products specifically categorized as corticosteroids, with oral exposure recorded. In terms of biological activity, it acts as an agonist/antagonist of two protein targets: the glucocorticoid receptor (NR3C1) and the mineralocorticoid receptor (NR3C2). C22H28O4 356.462 356.1987594 13209-41-1 [H][C@@]1(C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)C3=CC[C@]2(C)[C@@]1(O)C(=O)CO InChI=1/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3 ZYTXTXAMMDTYDQ-DGEXFFLYSA-N Detected and Not Quantified logp 2.54 average_mass 356.462 ChemAxon mono_mass 356.1987594 ChemAxon smiles [H][C@@]1(C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)C3=CC[C@]2(C)[C@@]1(O)C(=O)CO ChemAxon formula C22H28O4 ChemAxon inchi InChI=1/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3 ChemAxon inchikey ZYTXTXAMMDTYDQ-DGEXFFLYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226223680> DB15114 3035000 BE0000794 BE0000668