1.0 2026-04-05 10:44:28 UTC 2026-08-22 10:54:55 UTC Eluxadoline SmallMolecule Eluxadoline is an organic compound with the chemical formula C32H35N5O5. Eluxadoline belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 569.66 g/mol, Eluxadoline is a heavy molecule. This compound is found in healthcare, pharmaceuticals, and veterinary products, where it is classified as an antipropulsive. The recorded route of exposure for this substance is oral. At a molecular level, Eluxadoline acts upon three recorded protein targets, serving as an agonist/antagonist of the Mu-type opioid receptor (OPRM1), the Delta-type opioid receptor (OPRD1), and the Kappa-type opioid receptor (OPRK1). C32H35N5O5 569.662 569.2638192 864821-90-9 COC1=C(C=C(CN([C@@H](C)C2=NC=C(N2)C2=CC=CC=C2)C(=O)[C@@H](N)CC2=C(C)C=C(C=C2C)C(N)=O)C=C1)C(O)=O InChI=1S/C32H35N5O5/c1-18-12-23(29(34)38)13-19(2)24(18)15-26(33)31(39)37(17-21-10-11-28(42-4)25(14-21)32(40)41)20(3)30-35-16-27(36-30)22-8-6-5-7-9-22/h5-14,16,20,26H,15,17,33H2,1-4H3,(H2,34,38)(H,35,36)(H,40,41)/t20-,26-/m0/s1 QFNHIDANIVGXPE-FNZWTVRRSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Phenylalanine and derivatives Alkyl aryl ethers Alpha amino acid amides Amino acids Amphetamines and derivatives Anisoles Aralkylamines Azacyclic compounds Benzamides Benzoic acids Benzoyl derivatives Carbonyl compounds Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Imidazolyl carboxylic acids and derivatives Methoxybenzenes Monoalkylamines Monocarboxylic acids and derivatives O-methoxybenzoic acids and derivatives Organic oxides Organopnictogen compounds Phenoxy compounds Phenylimidazoles Primary carboxylic acid amides Tertiary carboxylic acid amides m-Xylenes 4-phenylimidazole 5-phenylimidazole Alkyl aryl ether Alpha-amino acid amide Amine Amino acid Amphetamine or derivatives Anisole Aralkylamine Aromatic heteromonocyclic compound Azacycle Azole Benzamide Benzenoid Benzoic acid Benzoic acid or derivatives Benzoyl Carbonyl group Carboxamide group Carboxylic acid Ether Heteroaromatic compound Hydrocarbon derivative Imidazole Imidazolyl carboxylic acid derivative M-xylene Methoxybenzene Monocarboxylic acid or derivatives Monocyclic benzene moiety O-methoxybenzoic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ether Phenoxy compound Phenylalanine or derivatives Primary aliphatic amine Primary amine Primary carboxylic acid amide Tertiary carboxylic acid amide Xylene Aromatic heteromonocyclic compounds L-phenylalanine derivative amino acid amide benzamides imidazoles methoxybenzoic acid Detected and Not Quantified Eluxadoline Action Pathway SMP0126838 Eluxadoline Drug Metabolism Action Pathway SMP0144394 Eluxadoline Predicted Metabolism Pathway SMP0174742 logp 1.8 average_mass 569.662 ChemAxon mono_mass 569.2638192 ChemAxon smiles COC1=C(C=C(CN([C@@H](C)C2=NC=C(N2)C2=CC=CC=C2)C(=O)[C@@H](N)CC2=C(C)C=C(C=C2C)C(N)=O)C=C1)C(O)=O ChemAxon formula C32H35N5O5 ChemAxon inchi InChI=1S/C32H35N5O5/c1-18-12-23(29(34)38)13-19(2)24(18)15-26(33)31(39)37(17-21-10-11-28(42-4)25(14-21)32(40)41)20(3)30-35-16-27(36-30)22-8-6-5-7-9-22/h5-14,16,20,26H,15,17,33H2,1-4H3,(H2,34,38)(H,35,36)(H,40,41)/t20-,26-/m0/s1 ChemAxon inchikey QFNHIDANIVGXPE-FNZWTVRRSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7273b0dd48> DB09272 11250029 BE0000770 BE0000420 BE0000632