<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-05 10:46:31 UTC</creation_date>
  <update_date>2026-05-14 16:55:00 UTC</update_date>
  <accession/>
  <common_name>Glycopyrronium</common_name>
  <class>SmallMolecule</class>
  <description>Glycopyrronium is an organic compound with the formula C19H28NO3 and an average molecular weight of 318.43 g/mol. Glycopyrronium belongs to the benzene and substituted derivatives, a class of benzenoids within the organic compounds.

This compound is found in or released from four recorded sources, including dermatological preparations, drugs for obstructive airway diseases, drugs for functional gastrointestinal disorders, and antispasmodics in combination with psycholeptics. It is associated with pharmaceuticals and veterinary products. Recorded exposure routes for glycopyrronium include oral, intravenous, intramuscular, respiratory, and topical administration.

At the molecular level, glycopyrronium interacts with five recorded protein targets. It acts as an antagonist of the Muscarinic acetylcholine receptor M1 (CHRM1), Muscarinic acetylcholine receptor M2 (CHRM2), Muscarinic acetylcholine receptor M3 (CHRM3), and Muscarinic acetylcholine receptor M4 (CHRM4), in addition to one other protein.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C19H28NO3</chemical_formula>
  <average_molecular_weight>318.4305</average_molecular_weight>
  <monisotopic_moleculate_weight>318.2069188</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>740028-90-4</cas_registry_number>
  <smiles>C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)C1=CC=CC=C1</smiles>
  <inchi>InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1/t17-,19-/m0/s1</inchi>
  <inchikey>ANGKOCUUWGHLCE-HKUYNNGSSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>-1.4</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>318.4305</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>318.2069188</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)C1=CC=CC=C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C19H28NO3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1/t17-,19-/m0/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>ANGKOCUUWGHLCE-HKUYNNGSSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726facb410&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB00986</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>9933193</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
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  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
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      <target_id>BE0000092</target_id>
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      <target_id>BE0000045</target_id>
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      <target_id>BE0000560</target_id>
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      <target_id>BE0000247</target_id>
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</compound>
