1.0 2026-04-05 10:48:52 UTC 2026-08-20 00:45:06 UTC Efinaconazole SmallMolecule Efinaconazole is an organic compound with the formula C18H22F2N4O and an average molecular weight of 348.40 g/mol. Efinaconazole belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds. The compound is recorded as being found in or released from three sources: antennas within electrical and electronic equipment, non electric simulated smoking devices among household cleaning and consumer products, and antifungals for dermatological use within healthcare, pharmaceuticals and veterinary products. The recorded route of exposure for this compound is topical. In terms of its biological activity, efinaconazole acts as an inhibitor of the protein target lanosterol 14-alpha demethylase (ERG11). C18H22F2N4O 348.398 348.1761678 164650-44-6 C[C@@H](N1CCC(=C)CC1)[C@](O)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1 InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1 NFEZZTICAUWDHU-RDTXWAMCSA-N Detected and Not Quantified Efinaconazole Action Pathway SMP0125813 Efinaconazole Drug Metabolism SMP0130898 Efinaconazole Drug Metabolism Action Pathway SMP0144264 logp 2.24 average_mass 348.398 ChemAxon mono_mass 348.1761678 ChemAxon smiles C[C@@H](N1CCC(=C)CC1)[C@](O)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1 ChemAxon formula C18H22F2N4O ChemAxon inchi InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1 ChemAxon inchikey NFEZZTICAUWDHU-RDTXWAMCSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baeec64b8> DB09040 489181 BE0000233