<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-05 11:20:28 UTC</creation_date>
  <update_date>2026-08-22 03:06:55 UTC</update_date>
  <accession/>
  <common_name>Ospemifene</common_name>
  <class>SmallMolecule</class>
  <description>Ospemifene is an organic compound with the formula C24H23ClO2 and an average molecular weight of 378.90 g/mol. Ospemifene belongs to the stilbenes, a class of phenylpropanoids and polyketides within the organic compounds. It is utilized in healthcare, pharmaceuticals, and veterinary products as a sex hormone and modulator of the genital system, with oral exposure being the recorded route. Regarding its pharmacological activity, it acts as both an agonist and antagonist of the Estrogen receptor (ESR1).</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C24H23ClO2</chemical_formula>
  <average_molecular_weight>378.9</average_molecular_weight>
  <monisotopic_moleculate_weight>378.1386577</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>128607-22-7</cas_registry_number>
  <smiles>OCCOC1=CC=C(C=C1)C(=C(\CCCl)C1=CC=CC=C1)\C1=CC=CC=C1</smiles>
  <inchi>InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-</inchi>
  <inchikey>LUMKVTFCDUIE-VHXPQNKSSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Ospemifene Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0143948</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>5.56</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>378.9</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>378.1386577</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>OCCOC1=CC=C(C=C1)C(=C(\CCCl)C1=CC=CC=C1)\C1=CC=CC=C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C24H23ClO2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>LUMKVTFCDUIE-VHXPQNKSSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7276dc6af0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB04938</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>3036505</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
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  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
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      <target_id>BE0000123</target_id>
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</compound>
