<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-05 11:26:53 UTC</creation_date>
  <update_date>2026-08-20 04:09:35 UTC</update_date>
  <accession/>
  <common_name>Gepirone</common_name>
  <class>SmallMolecule</class>
  <description>Gepirone is an organic compound with the chemical formula C19H29N5O2 and an average molecular weight of 359.47 g/mol. Gepirone belongs to the piperazines, a subclass of diazinanes within the organic compounds. It is classified as an organoheterocyclic compound.

In terms of biological activity, gepirone acts as an agonist and partial agonist of the 5-hydroxytryptamine receptor 1A (HTR1A). The compound is found in or released from five recorded sources, which include antidepressants within healthcare, pharmaceuticals, and veterinary products, as well as non-electric simulated smoking devices found in household cleaning and consumer products. Additionally, it is associated with electrical and electronic equipment, specifically antennas, radio transmission systems, and electrically stimulated smoking devices. The recorded exposure route for this compound is oral.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C19H29N5O2</chemical_formula>
  <average_molecular_weight>359.474</average_molecular_weight>
  <monisotopic_moleculate_weight>359.2321252</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>83928-76-1</cas_registry_number>
  <smiles>CC1(C)CC(=O)N(CCCCN2CCN(CC2)C2=NC=CC=N2)C(=O)C1</smiles>
  <inchi>InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3</inchi>
  <inchikey>QOIGKGMMAGJZNZ-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>1.35</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>359.474</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>359.2321252</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CC1(C)CC(=O)N(CCCCN2CCN(CC2)C2=NC=CC=N2)C(=O)C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C19H29N5O2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>QOIGKGMMAGJZNZ-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
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  <lethaldose/>
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  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721b6c3038&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB12184</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>55191</pubchem_compound_id>
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  <wikipidia/>
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</compound>
