1.0 2026-04-05 11:41:12 UTC 2026-08-22 03:31:50 UTC Givinostat SmallMolecule Givinostat is an organic compound with the chemical formula C24H27N3O4 and an average molecular weight of 421.50 g/mol. Givinostat belongs to the phenylcarbamic acid esters, a subclass of benzene and substituted derivatives within the organic compounds. This compound is recorded as being found in or released from one source: healthcare, pharmaceuticals & veterinary products, specifically drugs used for disorders of the musculo-skeletal system. The recorded route of exposure for this substance is oral. In terms of its biological activity, Givinostat acts on ten recorded protein targets. It serves as an inhibitor of histone deacetylase 1 (HDAC1), histone deacetylase 3 (HDAC3), histone deacetylase 4 (HDAC4), and histone deacetylase 7 (HDAC7), in addition to six other proteins. C24H27N3O4 421.497 421.2001563 497833-27-9 CCN(CC)CC1=CC2=C(C=C1)C=C(COC(=O)NC1=CC=C(C=C1)C(=O)NO)C=C2 InChI=1S/C24H27N3O4/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28) YALNUENQHAQXEA-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Phenylcarbamic acid esters Phenylcarbamic acid esters Aralkylamines Benzoic acids and derivatives Benzoyl derivatives Carbamate esters Carbonyl compounds Hydrocarbon derivatives Hydroxamic acids Naphthalenes Organic carbonic acids and derivatives Organic oxides Organopnictogen compounds Trialkylamines Amine Amino acid or derivatives Aralkylamine Aromatic homopolycyclic compound Benzoic acid or derivatives Benzoyl Carbamic acid ester Carbonic acid derivative Carbonyl group Carboxylic acid derivative Hydrocarbon derivative Hydroxamic acid Naphthalene Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenylcarbamic acid ester Tertiary aliphatic amine Tertiary amine Aromatic homopolycyclic compounds Detected and Not Quantified logp 3.51 average_mass 421.497 ChemAxon mono_mass 421.2001563 ChemAxon smiles CCN(CC)CC1=CC2=C(C=C1)C=C(COC(=O)NC1=CC=C(C=C1)C(=O)NO)C=C2 ChemAxon formula C24H27N3O4 ChemAxon inchi InChI=1S/C24H27N3O4/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28) ChemAxon inchikey YALNUENQHAQXEA-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72244d4e30> DB12645 9804992 BE0002367 BE0003523 BE0002365 BE0003525 BE0002366 BE0008667 BE0001608 BE0002368 BE0000881 BE0002408