1.0 2026-04-05 12:01:19 UTC 2026-08-21 19:57:39 UTC Tixocortol SmallMolecule Tixocortol is an organic compound with the formula C21H30O4S and an average molecular weight of 378.53 g/mol. Tixocortol belongs to the pregnane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound is found in or released from two recorded sources: healthcare, pharmaceuticals, and veterinary products, specifically as nasal preparations and intestinal antiinflammatory agents. Recorded exposure routes for the substance include rectal and cutaneous administration. Tixocortol acts on two recorded protein targets, serving as a binder/stimulator of the glucocorticoid receptor (NR3C1) and targeting histone deacetylase 2 (HDAC2). C21H30O4S 378.53 378.1864804 61951-99-3 [H][C@@]12CC[C@](O)(C(=O)CS)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C InChI=1S/C21H30O4S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-26)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 YWDBSCORAARPPF-VWUMJDOOSA-N Detected and Not Quantified Tixocortol Drug Metabolism SMP0130814 Tixocortol Drug Metabolism Action Pathway SMP0144303 logp 2.32 average_mass 378.53 ChemAxon mono_mass 378.1864804 ChemAxon smiles [H][C@@]12CC[C@](O)(C(=O)CS)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C ChemAxon formula C21H30O4S ChemAxon inchi InChI=1S/C21H30O4S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-26)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 ChemAxon inchikey YWDBSCORAARPPF-VWUMJDOOSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72a8c30bf0> DB09091 162955 BE0000794 BE0002366