1.0 2026-04-05 12:15:07 UTC 2026-08-22 04:04:08 UTC 17 Alpha-propionate SmallMolecule 17 Alpha-propionate belongs to the hydroxysteroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound has the formula C24H34O5 and an average molecular weight of 402.53 g/mol. It is found in anti-acne preparations used in healthcare, pharmaceuticals, and veterinary products, with recorded topical exposure routes. Regarding its biological activity, 17 Alpha-propionate acts as an antagonist of the Androgen receptor (AR). C24H34O5 402.531 402.2406242 19608-29-8 CCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(=O)CO InChI=1S/C24H34O5/c1-4-21(28)29-24(20(27)14-25)12-9-19-17-6-5-15-13-16(26)7-10-22(15,2)18(17)8-11-23(19,24)3/h13,17-19,25H,4-12,14H2,1-3H3/t17-,18+,19+,22+,23+,24+/m1/s1 GPNHMOZDMYNCPO-PDUMRIMRSA-N Detected and Not Quantified Clascoterone Drug Metabolism Action Pathway SMP0144868 Clascoterone Predicted Metabolism Pathway SMP0174699 logp 3.73 average_mass 402.531 ChemAxon mono_mass 402.2406242 ChemAxon smiles CCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(=O)CO ChemAxon formula C24H34O5 ChemAxon inchi InChI=1S/C24H34O5/c1-4-21(28)29-24(20(27)14-25)12-9-19-17-6-5-15-13-16(26)7-10-22(15,2)18(17)8-11-23(19,24)3/h13,17-19,25H,4-12,14H2,1-3H3/t17-,18+,19+,22+,23+,24+/m1/s1 ChemAxon inchikey GPNHMOZDMYNCPO-PDUMRIMRSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bafb0c448> DB12499 11750009 BE0000132