1.0 2026-04-05 12:21:07 UTC 2026-05-14 16:25:19 UTC Ibutilide SmallMolecule Ibutilide is an organic compound with the chemical formula C20H36N2O3S and an average molecular weight of 384.58 g/mol. Ibutilide belongs to the phenylbutylamines, a subclass of benzene and substituted derivatives within the organic compounds. This compound is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically within the antiarrhythmics of class I and III. The recorded route of exposure for this substance is intravenous. Ibutilide interacts with 10 recorded protein targets. These include the voltage-gated inwardly rectifying potassium channel KCNH6, for which it acts as an activator or inhibitor, as well as the voltage-dependent L-type calcium channel subunit beta-1 (CACNB1), the voltage-dependent calcium channel gamma-1 subunit (CACNG1), and the voltage-dependent calcium channel subunit alpha-2/delta-1 (CACNA2D1). Additionally, there are 6 other proteins identified as targets for this compound. C20H36N2O3S 384.58 384.244664 122647-31-8 CCCCCCCN(CC)CCC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1 InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3/t20-/m0/s1 ALOBUEHUHMBRLE-FQEVSTJZSA-N Detected and Not Quantified Ibutilide Action Pathway SMP0000332 Ibutilide Drug Metabolism Action Pathway SMP0142768 logp 2.54 average_mass 384.58 ChemAxon mono_mass 384.244664 ChemAxon smiles CCCCCCCN(CC)CCC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1 ChemAxon formula C20H36N2O3S ChemAxon inchi InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3/t20-/m0/s1 ChemAxon inchikey ALOBUEHUHMBRLE-FQEVSTJZSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727d557318> DB00308 24848689 BE0000462 BE0000303 BE0000679 BE0000691 BE0000090 BE0000430 BE0000154 BE0000680 BE0000708 BE0000699