1.0 2026-04-05 13:06:57 UTC 2026-08-22 07:40:56 UTC Fedratinib SmallMolecule Fedratinib is an organic compound with the chemical formula C27H36N6O3S. Fedratinib belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds. With an average molecular weight of 524.68 g/mol, Fedratinib is a heavy molecule. This compound is utilized in healthcare, pharmaceuticals, and veterinary products, specifically as an antineoplastic agent and gynecological product, and is administered via the oral exposure route. Fedratinib acts on three recorded protein targets, functioning as an inhibitor of Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK1, and Receptor-type tyrosine-protein kinase FLT3. C27H36N6O3S 524.68 524.25696 936091-26-8 CC1=CN=C(NC2=CC=C(OCCN3CCCC3)C=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31) JOOXLOJCABQBSG-UHFFFAOYSA-N Detected and Not Quantified Fedratinib Drug Metabolism Action Pathway SMP0144869 logp 4.64 average_mass 524.68 ChemAxon mono_mass 524.25696 ChemAxon smiles CC1=CN=C(NC2=CC=C(OCCN3CCCC3)C=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C ChemAxon formula C27H36N6O3S ChemAxon inchi InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31) ChemAxon inchikey JOOXLOJCABQBSG-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7227989748> DB12500 16722836 BE0002408 BE0000147 BE0004145