1.0 2026-04-05 13:38:45 UTC 2026-08-22 00:01:14 UTC Cyt-387 SmallMolecule Cyt-387 is an organic compound with the chemical formula C23H22N6O2 and an average molecular weight of 414.47 g/mol. Cyt-387 belongs to the pyrimidines and pyrimidine derivatives, a subclass of diazines within the organic compounds. Within the superclass of organoheterocyclic compounds, this substance is identified as an antineoplastic agent used in healthcare, pharmaceuticals, and veterinary products. It has been recorded as being administered via the oral exposure route. Cyt-387 acts on six recorded protein targets, serving as an inhibitor of Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, and Non-receptor tyrosine-protein kinase TYK2, as well as two other proteins. C23H22N6O2 414.469 414.1804239 1056634-68-4 O=C(NCC#N)C1=CC=C(C=C1)C1=CC=NC(NC2=CC=C(C=C2)N2CCOCC2)=N1 InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28) ZVHNDZWQTBEVRY-UHFFFAOYSA-N Detected and Not Quantified logp 2.7 average_mass 414.469 ChemAxon mono_mass 414.1804239 ChemAxon smiles O=C(NCC#N)C1=CC=C(C=C1)C1=CC=NC(NC2=CC=C(C=C2)N2CCOCC2)=N1 ChemAxon formula C23H22N6O2 ChemAxon inchi InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28) ChemAxon inchikey ZVHNDZWQTBEVRY-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721f7a3df0> DB11763 25062766 BE0004145 BE0002408 BE0003493 BE0004146 BE0000264 BE0000147