1.0 2026-04-05 13:47:51 UTC 2026-08-22 05:38:19 UTC Plazomicin SmallMolecule Plazomicin is an organic compound with the chemical formula C25H48N6O10. Plazomicin belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 592.69 g/mol, Plazomicin is a heavy molecule. This compound is found in healthcare, pharmaceuticals, and veterinary products as an aminoglycoside antibacterial, with intravenous administration as a recorded exposure route. Plazomicin acts on two recorded protein targets, functioning as an inhibitor of the mitochondrial rRNA methyltransferase 2 (MRM2) and the small ribosomal subunit protein uS14 (rpsN). C25H48N6O10 592.691 592.3431917 1154757-24-0 CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@@H](C[C@H](N)[C@@H](O[C@H]3OC(CNCCO)=CC[C@H]3N)[C@@H]2O)NC(=O)[C@@H](O)CCN)OC[C@]1(C)O InChI=1S/C25H48N6O10/c1-25(37)11-38-24(18(35)21(25)29-2)41-20-15(31-22(36)16(33)5-6-26)9-14(28)19(17(20)34)40-23-13(27)4-3-12(39-23)10-30-7-8-32/h3,13-21,23-24,29-30,32-35,37H,4-11,26-28H2,1-2H3,(H,31,36)/t13-,14+,15-,16+,17+,18-,19-,20+,21-,23-,24-,25+/m1/s1 IYDYFVUFSPQPPV-PEXOCOHZSA-N Detected and Not Quantified Plazomicin Action Pathway SMP0126287 Plazomicin Drug Metabolism Action Pathway SMP0144879 Plazomicin Predicted Metabolism Pathway SMP0174831 logp -6.1 average_mass 592.691 ChemAxon mono_mass 592.3431917 ChemAxon smiles CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@@H](C[C@H](N)[C@@H](O[C@H]3OC(CNCCO)=CC[C@H]3N)[C@@H]2O)NC(=O)[C@@H](O)CCN)OC[C@]1(C)O ChemAxon formula C25H48N6O10 ChemAxon inchi InChI=1S/C25H48N6O10/c1-25(37)11-38-24(18(35)21(25)29-2)41-20-15(31-22(36)16(33)5-6-26)9-14(28)19(17(20)34)40-23-13(27)4-3-12(39-23)10-30-7-8-32/h3,13-21,23-24,29-30,32-35,37H,4-11,26-28H2,1-2H3,(H,31,36)/t13-,14+,15-,16+,17+,18-,19-,20+,21-,23-,24-,25+/m1/s1 ChemAxon inchikey IYDYFVUFSPQPPV-PEXOCOHZSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225de30c0> DB12615 42613186 BE0003708 BE0020789