1.0 2026-04-05 13:49:52 UTC 2026-08-19 18:16:43 UTC Doravirine SmallMolecule Doravirine is an organic compound with the formula C17H11ClF3N5O3 and an average molecular weight of 425.75 g/mol. Doravirine belongs to the ethers, a subclass of organooxygen compounds within the organic compounds. This compound is recorded as being released from healthcare, pharmaceuticals, and veterinary products specifically as an antiviral, with oral exposure being the recorded route. In terms of biological activity, doravirine acts as an inhibitor of two protein targets: the Gag-Pol polyprotein (gag-pol) and Reverse transcriptase/RNaseH (pol). C17H11ClF3N5O3 425.75 425.0502516 1338225-97-0 CN1C(=O)NN=C1CN1C=CC(=C(OC2=CC(Cl)=CC(=C2)C#N)C1=O)C(F)(F)F InChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28) ZIAOVIPSKUPPQW-UHFFFAOYSA-N Detected and Not Quantified Doravirine Action Pathway SMP0125908 Doravirine Drug Metabolism Action Pathway SMP0144845 logp 2.23 average_mass 425.75 ChemAxon mono_mass 425.0502516 ChemAxon smiles CN1C(=O)NN=C1CN1C=CC(=C(OC2=CC(Cl)=CC(=C2)C#N)C1=O)C(F)(F)F ChemAxon formula C17H11ClF3N5O3 ChemAxon inchi InChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28) ChemAxon inchikey ZIAOVIPSKUPPQW-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7220670f18> DB12301 58460047 BE0004136 BE0002050