1.0 2026-04-05 13:49:57 UTC 2026-08-20 01:52:57 UTC Talazoparib SmallMolecule Talazoparib is an organic compound with the chemical formula C19H14F2N6O and an average molecular weight of 380.36 g/mol. Talazoparib belongs to the phenylquinolines, a subclass of quinolines and derivatives within the organic compounds. This compound is used as an antineoplastic agent within the sector of healthcare, pharmaceuticals, and veterinary products, with oral administration as the recorded exposure route. In terms of biological activity, talazoparib acts as an inhibitor of two protein targets: Poly [ADP-ribose] polymerase 1 (PARP1) and Poly [ADP-ribose] polymerase 2 (PARP2). C19H14F2N6O 380.359 380.1197155 1207456-01-6 CN1N=CN=C1[C@@H]1[C@H](NC2=C3C1=NNC(=O)C3=CC(F)=C2)C1=CC=C(F)C=C1 InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m1/s1 HWGQMRYQVZSGDQ-HZPDHXFCSA-N Detected and Not Quantified Talazoparib Drug Metabolism SMP0130871 Talazoparib Drug Metabolism Action Pathway SMP0144778 logp 2.11 average_mass 380.359 ChemAxon mono_mass 380.1197155 ChemAxon smiles CN1N=CN=C1[C@@H]1[C@H](NC2=C3C1=NNC(=O)C3=CC(F)=C2)C1=CC=C(F)C=C1 ChemAxon formula C19H14F2N6O ChemAxon inchi InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,24H,1H3,(H,26,28)/t15-,16-/m1/s1 ChemAxon inchikey HWGQMRYQVZSGDQ-HZPDHXFCSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7277712960> DB11760 135565082 BE0001717 BE0003798