1.0 2026-04-05 13:50:44 UTC 2026-08-22 08:47:12 UTC Lifitegrast SmallMolecule Lifitegrast is an organic compound with the chemical formula C29H24Cl2N2O7S. Lifitegrast belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 615.48 g/mol, Lifitegrast is a heavy molecule. This compound is identified as a protein target antagonist or inhibitor of Intercellular adhesion molecule 1 (ICAM1) and Integrin alpha-L (ITGAL). It is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically ophthalmologicals. The recorded exposure route for this substance is ophthalmic. C29H24Cl2N2O7S 615.48 614.0681275 1025967-78-5 CS(=O)(=O)C1=CC=CC(C[C@H](NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C2=CC3=C(C=CO3)C=C2)C(O)=O)=C1 InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1 JFOZKMSJYSPYLN-QHCPKHFHSA-N Detected and Not Quantified Lifitegrast Drug Metabolism Action Pathway SMP0144734 logp 4.02 average_mass 615.48 ChemAxon mono_mass 614.0681275 ChemAxon smiles CS(=O)(=O)C1=CC=CC(C[C@H](NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C2=CC3=C(C=CO3)C=C2)C(O)=O)=C1 ChemAxon formula C29H24Cl2N2O7S ChemAxon inchi InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1 ChemAxon inchikey JFOZKMSJYSPYLN-QHCPKHFHSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72279d14a8> DB11611 11965427 BE0000516 BE0001085