1.0 2026-04-05 13:54:16 UTC 2026-08-19 18:17:35 UTC 3-{3-[3,5-Bis(trifluoromethyl)phenyl]-1h-1,2,4-triazol-1-yl}-n'-(pyrazin-2-yl)prop-2-enehydrazide SmallMolecule 3-{3-[3,5-Bis(trifluoromethyl)phenyl]-1h-1,2,4-triazol-1-yl}-n'-(pyrazin-2-yl)prop-2-enehydrazide belongs to the triazoles, a subclass of azoles within the organic compounds. This organoheterocyclic compound has the chemical formula C17H10F6N6O and an average molecular weight of 443.31 g/mol. In terms of biological activity, it is recorded as an inhibitor of the protein target Exportin-1 (XPO1). The compound is found in or released from five recorded sources, including healthcare, pharmaceuticals, and veterinary products specifically as antineoplastic agents. Other identified sources include building and construction materials such as floors, food, food processing and cookware specifically molasses and the treatment of molasses, and electrical and electronic equipment including antennas and relays. The recorded route of exposure for this substance is oral. C17H10F6N6O 443.313 428.0820283 1393477-72-9 FC(F)(F)C1=CC(=CC(=C1)C1=NN(\C=C/C(=O)NNC2=NC=CN=C2)C=N1)C(F)(F)F InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1- DEVSOMFAQLZNKR-RJRFIUFISA-N Detected and Not Quantified Selinexor Drug Metabolism SMP0130780 Selinexor Drug Metabolism Action Pathway SMP0144804 logp 3.07 average_mass 443.313 ChemAxon mono_mass 428.0820283 ChemAxon smiles FC(F)(F)C1=CC(=CC(=C1)C1=NN(\C=C/C(=O)NNC2=NC=CN=C2)C=N1)C(F)(F)F ChemAxon formula C17H10F6N6O ChemAxon inchi InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1- ChemAxon inchikey DEVSOMFAQLZNKR-RJRFIUFISA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bbf983df0> DB11942 71481097 BE0009694