<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-05 14:01:23 UTC</creation_date>
  <update_date>2026-08-19 04:22:15 UTC</update_date>
  <accession/>
  <common_name>2-{[5-(3-Chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid</common_name>
  <class>SmallMolecule</class>
  <description>2-{[5-(3-Chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. This compound has the chemical formula $\text{C}_{14}\text{H}_{11}\text{ClN}_2\text{O}_4$ and an average molecular weight of 306.70 g/mol.

In terms of its biological activity, the compound acts upon five recorded protein targets. It functions as an inhibitor or stabilization agent for Prolyl hydroxylase EGLN2, Prolyl hydroxylase EGLN3, Egl nine homolog 1 (EGLN1), and Hypoxia-inducible factor 1-alpha (HIF1A), in addition to one other protein. Regarding its application and occurrence, it is found in or released from one recorded source: healthcare, pharmaceuticals, and veterinary products, specifically within antianemic preparations. The recorded route of exposure for this compound is oral.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C14H11ClN2O4</chemical_formula>
  <average_molecular_weight>306.7</average_molecular_weight>
  <monisotopic_moleculate_weight>306.0407345</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>1000025-07-9</cas_registry_number>
  <smiles>OC(=O)CNC(=O)C1=C(O)C=C(C=N1)C1=CC(Cl)=CC=C1</smiles>
  <inchi>InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)</inchi>
  <inchikey>JGRXMPYUTJLTKT-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>2.2</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>306.7</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>306.0407345</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>OC(=O)CNC(=O)C1=C(O)C=C(C=N1)C1=CC(Cl)=CC=C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C14H11ClN2O4</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>JGRXMPYUTJLTKT-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f723c31c800&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB12255</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>23634441</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
    <target>
      <target_id/>
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      <target_id>BE0002219</target_id>
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      <target_id>BE0009679</target_id>
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</compound>
