1.0 2026-04-05 14:02:08 UTC 2026-08-22 07:40:09 UTC Methyl 3-(2-{[4-cyano-4-(3,4-dimethoxyphenyl)-4-(propan-2-yl)butyl](methyl)amino}ethyl)benzoate SmallMolecule Methyl 3-(2-{[4-cyano-4-(3,4-dimethoxyphenyl)-4-(propan-2-yl)butyl](methyl)amino}ethyl)benzoate belongs to the phenylbutylamines, a subclass of benzene and substituted derivatives within the organic compounds. This compound has the chemical formula C27H36N2O4 and an average molecular weight of 452.60 g/mol. In terms of its application and occurrence, the compound is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically as a calcium channel blocker. The recorded exposure route for this substance is nasal. The compound interacts with nine recorded protein targets. It acts as a blocker of the Voltage-dependent L-type calcium channel subunit beta-4 (CACNB4), Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A), Voltage-dependent L-type calcium channel subunit alpha-1F (CACNA1F), and Voltage-dependent L-type calcium channel subunit beta-3 (CACNB3), in addition to five other proteins. C27H36N2O4 452.595 452.2675076 1593673-23-4 COC(=O)C1=CC(CCN(C)CCC[C@](C#N)(C(C)C)C2=CC=C(OC)C(OC)=C2)=CC=C1 InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1 VAZNEHLGJGSQEL-MHZLTWQESA-N Detected and Not Quantified logp 5.36 average_mass 452.595 ChemAxon mono_mass 452.2675076 ChemAxon smiles COC(=O)C1=CC(CCN(C)CCC[C@](C#N)(C(C)C)C2=CC=C(OC)C(OC)=C2)=CC=C1 ChemAxon formula C27H36N2O4 ChemAxon inchi InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1 ChemAxon inchikey VAZNEHLGJGSQEL-MHZLTWQESA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf8b79c48> DB12605 91824132 BE0002356 BE0000356 BE0002357 BE0002358 BE0002359 BE0000303 BE0002354 BE0002355 BE0000430