1.0 2026-04-05 15:30:58 UTC 2026-08-22 06:25:06 UTC Ketoconazole, (2S,4R)- SmallMolecule Ketoconazole, (2S,4R)- belongs to the piperazines, a subclass of diazinanes within the organic compounds. With an average molecular weight of 531.43 g/mol, Ketoconazole, (2S,4R)- is a heavy molecule with the formula C26H28Cl2N4O4. Biologically, it functions as an inhibitor (PMC5824109) and an antifungal agent (PMC10162950). It acts on five recorded protein targets, serving as an inhibitor of Lanosterol 14-alpha demethylase (CYP51A1), Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1), Cytochrome P450 11B1, mitochondrial (CYP11B1), Cytochrome P450 11B2, mitochondrial (CYP11B2), and one other protein. This compound is found in or released from four recorded sources, including healthcare, pharmaceuticals & veterinary products such as antiadrenal preparations, and household cleaning & consumer products including bleaching agents. It is also associated with electrical & electronic equipment, specifically television systems and electric switches. The recorded route of exposure for this compound is oral. C26H28Cl2N4O4 531.43 530.1487607 142128-57-2 CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1 InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 XMAYWYJOQHXEEK-ZEQKJWHPSA-N Detected and Not Quantified logp 4.19 average_mass 531.43 ChemAxon mono_mass 530.1487607 ChemAxon smiles CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1 ChemAxon formula C26H28Cl2N4O4 ChemAxon inchi InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 ChemAxon inchikey XMAYWYJOQHXEEK-ZEQKJWHPSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f724402fd38> DB05667 47576 BE0000731 BE0000875 BE0000344 BE0003542 BE0003537