1.0 2026-04-06 04:11:28 UTC 2026-08-20 05:26:43 UTC Flibanserin SmallMolecule Flibanserin is an organic compound with the formula C20H21F3N4O and an average molecular weight of 390.41 g/mol. Flibanserin belongs to the piperazines, a subclass of diazinanes within the organic compounds. It is classified within the superclass of organoheterocyclic compounds. The compound is found in or released from healthcare, pharmaceuticals, and veterinary products specifically categorized as gynecologicals, with oral administration as the recorded exposure route. In terms of pharmacological activity, flibanserin interacts with three recorded protein targets. It acts as an agonist/agonist and antagonist/antagonist of the 5-hydroxytryptamine receptor 1A (HTR1A), the 5-hydroxytryptamine receptor 2A (HTR2A), and the D(4) dopamine receptor (DRD4). C20H21F3N4O 390.41 390.166746 167933-07-5 FC(F)(F)C1=CC=C(C=C1)N1CCN(CCN2C(=O)NC3=CC=CC=C23)CC1 InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28) PPRRDFIXUUSXRA-UHFFFAOYSA-N Detected and Not Quantified Flibanserin Serotonin Action Action Pathway SMP0126786 Flibanserin Drug Metabolism Action Pathway SMP0143942 logp 3.83 average_mass 390.41 ChemAxon mono_mass 390.166746 ChemAxon smiles FC(F)(F)C1=CC=C(C=C1)N1CCN(CCN2C(=O)NC3=CC=CC=C23)CC1 ChemAxon formula C20H21F3N4O ChemAxon inchi InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28) ChemAxon inchikey PPRRDFIXUUSXRA-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727c94dae0> DB04908 6918248 5293454 BE0000291 BE0000451 BE0000389