1.0 2026-04-06 04:19:35 UTC 2026-08-20 05:12:36 UTC Dolutegravir SmallMolecule Dolutegravir is an organic compound with the formula C20H19F2N3O5 and an average molecular weight of 419.38 g/mol. Dolutegravir belongs to the pyridinecarboxylic acids and derivatives, a subclass of pyridines and derivatives within the organic compounds. This compound is recorded as being found in or released from healthcare, pharmaceuticals, and veterinary products, specifically as an antiviral. The recorded route of exposure for this substance is oral. In terms of biological activity, dolutegravir acts upon two recorded protein targets: the Gag-Pol polyprotein (gag-pol) and as an inhibitor/modulator of the Gag-Pol polyprotein. C20H19F2N3O5 419.385 419.1292771 1051375-16-6 [H][C@]12CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(O)=C3C(=O)N1[C@H](C)CCO2 InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 RHWKPHLQXYSBKR-BMIGLBTASA-N Detected and Not Quantified Dolutegravir Action Pathway SMP0125912 Dolutegravir Drug Metabolism Action Pathway SMP0144224 logp 1.1 average_mass 419.385 ChemAxon mono_mass 419.1292771 ChemAxon smiles [H][C@]12CN3C=C(C(=O)NCC4=C(F)C=C(F)C=C4)C(=O)C(O)=C3C(=O)N1[C@H](C)CCO2 ChemAxon formula C20H19F2N3O5 ChemAxon inchi InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 ChemAxon inchikey RHWKPHLQXYSBKR-BMIGLBTASA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72678f0828> DB08930 54726191 BE0004855 BE0002050