<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-06 09:09:25 UTC</creation_date>
  <update_date>2026-08-20 06:16:03 UTC</update_date>
  <accession/>
  <common_name>Traxoprodil</common_name>
  <class>SmallMolecule</class>
  <description>Traxoprodil is an organic compound with the formula C20H25NO3 and an average molecular weight of 327.42 g/mol. Traxoprodil belongs to the phenylpiperidines, a subclass of piperidines within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds. Regarding its biological activity, there is one recorded protein target for this compound, as it acts as an antagonist of the Glutamate receptor ionotropic, NMDA 2B (GRIN2B).

The compound has been identified in or released from 19 recorded sources across multiple sectors. Within electrical and electronic equipment, it is found in capacitors, cell phones, batteries, printed circuit boards, wires and cables, and six additional sources. In the sector of textiles, leather and furnishings, it is associated with synthetic textiles as well as carpets and rugs. Its presence is also noted in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, it is found in lubricants used in both energy, oil and gas, as well as industrial manufacturing and chemical processing, along with two other sectors. Recorded routes of exposure for traxoprodil include touch, oral, and inhalation.</description>
  <categories/>
  <types>
    <type>PFAS</type>
  </types>
  <synonyms/>
  <chemical_formula>C20H25NO3</chemical_formula>
  <average_molecular_weight>327.424</average_molecular_weight>
  <monisotopic_moleculate_weight>327.183443669</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>134234-12-1</cas_registry_number>
  <smiles>C[C@@H]([C@@H](O)C1=CC=C(O)C=C1)N1CCC(O)(CC1)C1=CC=CC=C1</smiles>
  <inchi>InChI=1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1</inchi>
  <inchikey>QEMSVZNTSXPFJA-HYVOBHSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>2.3</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>327.424</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>327.183443669</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>C[C@@H]([C@@H](O)C1=CC=C(O)C=C1)N1CCC(O)(CC1)C1=CC=CC=C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C20H25NO3</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>QEMSVZNTSXPFJA-HYVOBHSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726c56c1c0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB18795</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>219101</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
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  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
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  <pdb_id/>
  <wikipidia/>
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</compound>
