<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-13 22:06:03 UTC</creation_date>
  <update_date>2026-05-14 17:47:36 UTC</update_date>
  <accession/>
  <common_name>Metribolone</common_name>
  <class>SmallMolecule</class>
  <description>Metribolone is an organic compound with the chemical formula C19H24O2 and an average molecular weight of 284.39 g/mol. Metribolone belongs to the estrane steroids, a subclass of steroids and steroid derivatives within the organic compounds.

This compound interacts with five recorded protein targets. It functions as an activator or inhibitor of the androgen receptor (AR), progesterone receptor (PGR), mineralocorticoid receptor (NR3C2), and nuclear receptor coactivator 2 (NCOA2), as well as one other protein.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C19H24O2</chemical_formula>
  <average_molecular_weight>284.3927</average_molecular_weight>
  <monisotopic_moleculate_weight>284.177630012</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>965-93-5</cas_registry_number>
  <smiles>[H][C@@]12CC[C@](C)(O)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H]</smiles>
  <inchi>InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1</inchi>
  <inchikey>CCCIJQPRIXGQOE-XWSJACJDSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>2.53</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>284.3927</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>284.177630012</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>[H][C@@]12CC[C@](C)(O)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H]</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C19H24O2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>CCCIJQPRIXGQOE-XWSJACJDSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721f7619a0&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB02998</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>261000</pubchem_compound_id>
  <chembl_id/>
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  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
    <target>
      <target_id/>
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      <target_id>BE0000132</target_id>
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  </targets>
</compound>
