1.0 2026-04-14 15:23:39 UTC 2026-08-20 02:07:43 UTC Roxadustat SmallMolecule Roxadustat is an organic compound with the formula C19H16N2O5 and an average molecular weight of 352.35 g/mol. Roxadustat belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. This compound is used in healthcare, pharmaceuticals, and veterinary products as part of antianemic preparations and is administered via the oral exposure route. It acts on three recorded protein targets, serving as an inhibitor of Egl nine homolog 1 (EGLN1) as well as Prolyl hydroxylase EGLN2 and Prolyl hydroxylase EGLN3. C19H16N2O5 352.346 352.105921623 808118-40-3 CC1=NC(C(=O)NCC(O)=O)=C(O)C2=C1C=C(OC1=CC=CC=C1)C=C2 InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23) YOZBGTLTNGAVFU-UHFFFAOYSA-N Detected and Not Quantified Roxadustat Drug Metabolism Action Pathway SMP0143929 logp 1.85 average_mass 352.346 ChemAxon mono_mass 352.105921623 ChemAxon smiles CC1=NC(C(=O)NCC(O)=O)=C(O)C2=C1C=C(OC1=CC=CC=C1)C=C2 ChemAxon formula C19H16N2O5 ChemAxon inchi InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23) ChemAxon inchikey YOZBGTLTNGAVFU-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72705ba3d0> DB04847 11256664 BE0002217 BE0002211 BE0002219