<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-14 15:57:53 UTC</creation_date>
  <update_date>2026-05-14 18:17:27 UTC</update_date>
  <accession/>
  <common_name>Cariprazine</common_name>
  <class>SmallMolecule</class>
  <description>Cariprazine is an organic compound with the chemical formula C21H32Cl2N4O and an average molecular weight of 427.41 g/mol. Cariprazine belongs to the piperazines, a subclass of diazinanes within the organic compounds. It is classified as an organoheterocyclic compound.

This compound is found in or released from one recorded source: healthcare, pharmaceuticals &amp; veterinary products, specifically as an antipsychotic. The recorded route of exposure is oral. Cariprazine interacts with eight recorded protein targets. It acts as an antagonist or partial agonist of the D(2) dopamine receptor (DRD2), the D(3) dopamine receptor (DRD3), the 5-hydroxytryptamine receptor 1A (HTR1A), and the 5-hydroxytryptamine receptor 2B (HTR2B). Additionally, it targets four other proteins.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C21H32Cl2N4O</chemical_formula>
  <average_molecular_weight>427.41</average_molecular_weight>
  <monisotopic_moleculate_weight>426.1953171</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>839712-12-8</cas_registry_number>
  <smiles>CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1</smiles>
  <inchi>InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-</inchi>
  <inchikey>KPWSJANDNDDRMB-QAQDUYKDSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>4.06</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>427.41</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>426.1953171</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C21H32Cl2N4O</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>KPWSJANDNDDRMB-QAQDUYKDSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
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  <metabolism/>
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  <lethaldose/>
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  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726f785e68&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB06016</drugbank_id>
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</compound>
