1.0 2026-04-14 18:23:53 UTC 2026-08-21 18:03:25 UTC Bictegravir SmallMolecule Bictegravir is an organic compound with the formula C21H18F3N3O5 and an average molecular weight of 449.39 g/mol. Bictegravir belongs to the pyridinecarboxylic acids and derivatives, a subclass of pyridines and derivatives within the organic compounds. It is further classified as an organoheterocyclic compound. The compound is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products (antivirals). The recorded exposure route for this substance is oral. Bictegravir acts on two recorded protein targets, serving as an antagonist of the Gag-Pol polyprotein and Reverse transcriptase/RNaseH (pol). C21H18F3N3O5 449.386 449.119855181 1611493-60-7 OC1=C2N(C[C@H]3O[C@@H]4CC[C@@H](C4)N3C2=O)C=C(C(=O)NCC2=C(F)C=C(F)C=C2F)C1=O InChI=1S/C21H18F3N3O5/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30)/t10-,11+,16+/m0/s1 SOLUWJRYJLAZCX-LYOVBCGYSA-N Detected and Not Quantified Bictegravir Action Pathway SMP0125910 Bictegravir Drug Metabolism Action Pathway SMP0144784 logp 1.36 average_mass 449.386 ChemAxon mono_mass 449.119855181 ChemAxon smiles OC1=C2N(C[C@H]3O[C@@H]4CC[C@@H](C4)N3C2=O)C=C(C(=O)NCC2=C(F)C=C(F)C=C2F)C1=O ChemAxon formula C21H18F3N3O5 ChemAxon inchi InChI=1S/C21H18F3N3O5/c22-9-3-14(23)12(15(24)4-9)6-25-20(30)13-7-26-8-16-27(10-1-2-11(5-10)32-16)21(31)17(26)19(29)18(13)28/h3-4,7,10-11,16,29H,1-2,5-6,8H2,(H,25,30)/t10-,11+,16+/m0/s1 ChemAxon inchikey SOLUWJRYJLAZCX-LYOVBCGYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72244c4a80> DB11799 90311989 BE0004136 BE0004855