<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-14 19:54:53 UTC</creation_date>
  <update_date>2026-08-18 00:58:42 UTC</update_date>
  <accession/>
  <common_name>Solriamfetol</common_name>
  <class>SmallMolecule</class>
  <description>Solriamfetol is an organic compound with the formula C10H14N2O2 and an average molecular weight of 194.23 g/mol. Solriamfetol belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds.

This compound is found in or released from one recorded source: healthcare, pharmaceuticals &amp; veterinary products, specifically as psychostimulants, agents used for adhd and nootropics. The recorded exposure route for this substance is oral. Solriamfetol acts on two recorded protein targets, serving as an inhibitor of the sodium-dependent dopamine transporter (SLC6A3) and the sodium-dependent noradrenaline transporter (SLC6A2).</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C10H14N2O2</chemical_formula>
  <average_molecular_weight>194.234</average_molecular_weight>
  <monisotopic_moleculate_weight>194.105527699</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>178429-62-4</cas_registry_number>
  <smiles>N[C@@H](COC(N)=O)CC1=CC=CC=C1</smiles>
  <inchi>InChI=1S/C10H14N2O2/c11-9(7-14-10(12)13)6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H2,12,13)/t9-/m1/s1</inchi>
  <inchikey>UCTRAOBQFUDCSR-SECBINFHSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Solriamfetol Action Pathway</name>
      <smpdb_id>SMP0126346</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Solriamfetol Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0145220</smpdb_id>
      <kegg_map_id/>
    </pathway>
    <pathway>
      <name>Solriamfetol Predicted Metabolism Pathway</name>
      <smpdb_id>SMP0174557</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>0.86</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>194.234</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>194.105527699</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>N[C@@H](COC(N)=O)CC1=CC=CC=C1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C10H14N2O2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C10H14N2O2/c11-9(7-14-10(12)13)6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H2,12,13)/t9-/m1/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>UCTRAOBQFUDCSR-SECBINFHSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226929a60&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB14754</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>10130337</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
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  <chebi_id/>
  <biocyc_id/>
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  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
    <target>
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      <target_id>BE0000486</target_id>
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</compound>
