1.0 2026-04-14 19:57:54 UTC 2026-08-21 18:55:38 UTC Filgotinib SmallMolecule Filgotinib is an organic compound with the formula C21H23N5O3S and an average molecular weight of 425.51 g/mol. Filgotinib belongs to the phenylpyridines, a subclass of pyridines and derivatives within the organic compounds. In terms of biological activity, it functions as an inhibitor of the protein target Tyrosine-protein kinase JAK1. The compound is found in or released from two recorded sources: electric hearing aids (Electrical & Electronic Equipment) and immunosuppressants (Healthcare, pharmaceuticals & veterinary products). The recorded route of exposure for this substance is oral. C21H23N5O3S 425.51 425.152160795 1206161-97-8 O=C(NC1=NN2C(C=CC=C2C2=CC=C(CN3CCS(=O)(=O)CC3)C=C2)=N1)C1CC1 InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27) RIJLVEAXPNLDTC-UHFFFAOYSA-N Detected and Not Quantified Filgotinib Drug Metabolism Action Pathway SMP0145226 logp 2.03 average_mass 425.51 ChemAxon mono_mass 425.152160795 ChemAxon smiles O=C(NC1=NN2C(C=CC=C2C2=CC=C(CN3CCS(=O)(=O)CC3)C=C2)=N1)C1CC1 ChemAxon formula C21H23N5O3S ChemAxon inchi InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27) ChemAxon inchikey RIJLVEAXPNLDTC-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7227405d30> DB14845 49831257 BE0004145