1.0 2026-04-14 20:02:05 UTC 2026-05-14 19:46:57 UTC Abrocitinib SmallMolecule Abrocitinib is an organic compound with the formula C14H21N5O2S and an average molecular weight of 323.42 g/mol. Abrocitinib belongs to the pyrrolo[2,3-d]pyrimidines, a subclass of pyrrolopyrimidines within the organic compounds. This compound is classified as an organoheterocyclic compound. In terms of its biological activity, abrocitinib acts as an inhibitor of four protein targets: Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, and Non-receptor tyrosine-protein kinase TYK2. Regarding its use and exposure, it is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically dermatological preparations. The recorded route of exposure for this compound is oral. C14H21N5O2S 323.42 323.14159611 1622902-68-4 CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)C1=C2C=CNC2=NC=N1 InChI=1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+ IUEWXNHSKRWHDY-PHIMTYICSA-N Detected and Not Quantified logp 0.83 average_mass 323.42 ChemAxon mono_mass 323.14159611 ChemAxon smiles CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)C1=C2C=CNC2=NC=N1 ChemAxon formula C14H21N5O2S ChemAxon inchi InChI=1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+ ChemAxon inchikey IUEWXNHSKRWHDY-PHIMTYICSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7227a5f3c0> DB14973 BE0004145 BE0002408 BE0003493 BE0004146