1.0 2026-04-14 20:03:17 UTC 2026-08-22 11:08:22 UTC Avacopan SmallMolecule Avacopan is an organic compound with the chemical formula C33H35F4N3O2. Avacopan belongs to the benzoyl derivatives, a subclass of benzene and substituted derivatives within the organic compounds. With an average molecular weight of 581.66 g/mol, Avacopan is a heavy molecule. In terms of biological activity, this compound acts as an antagonist of the C5a anaphylatoxin chemotactic receptor 1 (C5AR1). Avacopan is found in or released from two recorded sources: healthcare, pharmaceuticals & veterinary products, specifically as an immunosuppressant, and household cleaning & consumer products, specifically soap dispensers. The recorded exposure route for the compound is oral. C33H35F4N3O2 581.656 581.266540031 1346623-17-3 CC1=CC=C(NC(=O)[C@H]2CCCN([C@H]2C2=CC=C(NC3CCCC3)C=C2)C(=O)C2=C(F)C=CC=C2C)C=C1C(F)(F)F InChI=1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/h5,7,11-17,19,23,26,30,38H,3-4,6,8-10,18H2,1-2H3,(H,39,41)/t26-,30-/m0/s1 PUKBOVABABRILL-YZNIXAGQSA-N Detected and Not Quantified Avacopan Drug Metabolism Action Pathway SMP0145235 logp 7.59 average_mass 581.656 ChemAxon mono_mass 581.266540031 ChemAxon smiles CC1=CC=C(NC(=O)[C@H]2CCCN([C@H]2C2=CC=C(NC3CCCC3)C=C2)C(=O)C2=C(F)C=CC=C2C)C=C1C(F)(F)F ChemAxon formula C33H35F4N3O2 ChemAxon inchi InChI=1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/h5,7,11-17,19,23,26,30,38H,3-4,6,8-10,18H2,1-2H3,(H,39,41)/t26-,30-/m0/s1 ChemAxon inchikey PUKBOVABABRILL-YZNIXAGQSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226baad20> DB15011 49841217 BE0010095