1.0 2026-04-14 20:06:22 UTC 2026-08-22 03:30:24 UTC Pemigatinib SmallMolecule Pemigatinib is an organic compound with the chemical formula C24H27F2N5O4 and an average molecular weight of 487.51 g/mol. Pemigatinib belongs to the methoxybenzenes, a subclass of benzene and substituted derivatives within the organic compounds. This compound acts as an inhibitor of four protein targets: Fibroblast growth factor receptor 1 (FGFR1), Fibroblast growth factor receptor 2 (FGFR2), Fibroblast growth factor receptor 3 (FGFR3), and Fibroblast growth factor receptor 4 (FGFR4). Regarding its applications and presence, it is found in or released from eight recorded sources. These include healthcare, pharmaceuticals, and veterinary products, where it is used as an antineoplastic agent. Additionally, it is associated with electrical and electronic equipment, specifically amplifiers, antennas, electric hearing aids, line transmission systems, microphones, and two other sources. The recorded route of exposure for this compound is oral. C24H27F2N5O4 487.508 487.203110695 1513857-77-6 CCN1C(=O)N(CC2=CN=C3NC(CN4CCOCC4)=CC3=C12)C1=C(F)C(OC)=CC(OC)=C1F InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28) HCDMJFOHIXMBOV-UHFFFAOYSA-N Detected and Not Quantified Pemigatinib Drug Metabolism Action Pathway SMP0145239 Pemigatinib Predicted Metabolism Pathway SMP0174671 logp 1.82 average_mass 487.508 ChemAxon mono_mass 487.203110695 ChemAxon smiles CCN1C(=O)N(CC2=CN=C3NC(CN4CCOCC4)=CC3=C12)C1=C(F)C(OC)=CC(OC)=C1F ChemAxon formula C24H27F2N5O4 ChemAxon inchi InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28) ChemAxon inchikey HCDMJFOHIXMBOV-UHFFFAOYSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726c4e2268> DB15102 86705695 BE0002131 BE0000748 BE0002133 BE0001203