1.0 2026-04-14 20:41:56 UTC 2026-08-22 02:54:34 UTC Nedisertib SmallMolecule Nedisertib is an organic compound with the chemical formula C24H21ClFN5O3 and an average molecular weight of 481.91 g/mol. Nedisertib belongs to the pyrimidines and pyrimidine derivatives, a subclass of diazines within the organic compounds. It is further classified as an organoheterocyclic compound. Regarding its biological activity, Nedisertib acts as an inhibitor of the DNA-dependent protein kinase catalytic subunit (PRKDC). The compound has been recorded as being found in or released from two sources: antennas and line transmission systems within electrical and electronic equipment. C24H21ClFN5O3 481.91 481.1316954 1637542-33-6 COC1=NN=C(C=C1)[C@@H](O)C1=C(Cl)C=C(F)C(=C1)C1=NC=NC2=C1C=CC(=C2)N1CCOCC1 InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1 MOWXJLUYGFNTAL-DEOSSOPVSA-N Detected and Not Quantified logp 3.58 average_mass 481.91 ChemAxon mono_mass 481.1316954 ChemAxon smiles COC1=NN=C(C=C1)[C@@H](O)C1=C(Cl)C=C(F)C(=C1)C1=NC=NC2=C1C=CC(=C2)N1CCOCC1 ChemAxon formula C24H21ClFN5O3 ChemAxon inchi InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1 ChemAxon inchikey MOWXJLUYGFNTAL-DEOSSOPVSA-N ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb404d520> DB16252 86292849 BE0002385