<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2026-04-14 20:42:20 UTC</creation_date>
  <update_date>2026-08-22 12:03:54 UTC</update_date>
  <accession/>
  <common_name>Odevixibat</common_name>
  <class>SmallMolecule</class>
  <description>Odevixibat is a chemical compound with the molecular formula C37H48N4O8S2. Odevixibat belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 740.93 g/mol, Odevixibat is a heavy molecule.

The compound is an inhibitor of the ileal sodium/bile acid cotransporter (SLC10A2). Its recorded exposure route is oral. Odevixibat is found in or released from 17 recorded sources across several diverse categories. In the realm of healthcare, pharmaceuticals, and veterinary products, it is associated with bile therapy. Within the food, food processing, and cookware sector, it is linked to the preparation of wort. It is also identified in household cleaning and consumer products, specifically pipe accessories and other smoking requisites.

Furthermore, Odevixibat is recorded in building and construction materials, including ceilings and sunshades, awnings, or outside screens. It is also present in electrical and electronic equipment, appearing in antennas, amplifiers, electric hearing aids, auxiliary devices, and cores, yokes, or armatures, among six other sources.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>C37H48N4O8S2</chemical_formula>
  <average_molecular_weight>740.93</average_molecular_weight>
  <monisotopic_moleculate_weight>740.29135687</monisotopic_moleculate_weight>
  <iupac_name/>
  <traditional_iupac/>
  <cas_registry_number>501692-44-0</cas_registry_number>
  <smiles>CCCCC1(CCCC)CN(C2=CC=CC=C2)C2=CC(SC)=C(OCC(=O)N[C@@H](C(=O)N[C@@H](CC)C(O)=O)C3=CC=C(O)C=C3)C=C2S(=O)(=O)N1</smiles>
  <inchi>InChI=1S/C37H48N4O8S2/c1-5-8-19-37(20-9-6-2)24-41(26-13-11-10-12-14-26)29-21-31(50-4)30(22-32(29)51(47,48)40-37)49-23-33(43)39-34(25-15-17-27(42)18-16-25)35(44)38-28(7-3)36(45)46/h10-18,21-22,28,34,40,42H,5-9,19-20,23-24H2,1-4H3,(H,38,44)(H,39,43)(H,45,46)/t28-,34+/m0/s1</inchi>
  <inchikey>XULSCZPZVQIMFM-IPZQJPLYSA-N</inchikey>
  <taxonomy>
    <kingdom/>
    <super_class/>
    <class/>
    <sub_class/>
    <direct_parent/>
    <alternate_parents/>
    <substituents/>
    <molecular_framework/>
    <descriptors/>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways>
    <pathway>
      <name>Odevixibat Drug Metabolism Action Pathway</name>
      <smpdb_id>SMP0145290</smpdb_id>
      <kegg_map_id/>
    </pathway>
  </pathways>
  <state/>
  <appearance/>
  <experimental_properties>
    <property>
      <kind>logp</kind>
      <value>6.28</value>
    </property>
  </experimental_properties>
  <predicted_properties>
    <property>
      <kind>average_mass</kind>
      <value>740.93</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>740.29135687</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>CCCCC1(CCCC)CN(C2=CC=CC=C2)C2=CC(SC)=C(OCC(=O)N[C@@H](C(=O)N[C@@H](CC)C(O)=O)C3=CC=C(O)C=C3)C=C2S(=O)(=O)N1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>C37H48N4O8S2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/C37H48N4O8S2/c1-5-8-19-37(20-9-6-2)24-41(26-13-11-10-12-14-26)29-21-31(50-4)30(22-32(29)51(47,48)40-37)49-23-33(43)39-34(25-15-17-27(42)18-16-25)35(44)38-28(7-3)36(45)46/h10-18,21-22,28,34,40,42H,5-9,19-20,23-24H2,1-4H3,(H,38,44)(H,39,43)(H,45,46)/t28-,34+/m0/s1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>XULSCZPZVQIMFM-IPZQJPLYSA-N</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726757b9b8&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id>DB16261</drugbank_id>
  <hmdb_id/>
  <pubchem_compound_id>10153627</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets>
    <target>
      <target_id/>
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    <target>
      <target_id>BE0003643</target_id>
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  </targets>
</compound>
